Choroidal Venous Congestion Following Scleral Buckling - An Imaging Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Post operative choroidal venous congestion
研究概览
简要总结
This study aims to understand how blood flow at the back of the eye changes over time after this surgery. By studying these changes, the investigators hope to gain insights that could help improve the understanding of other eye diseases, such as age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy(PCV). This research may contribute to better treatments and outcomes for future patients.
详细描述
Scleral Buckling (SB) surgery emplaces a silicone band along the circumference of the eye to create an external support for retinal breaks, hence treating the retinal detachment. The investigators hypothesize that the presence of an external silicone band from the SB surgery would result in an increase in resistance across the choroidal venous outflow channels. This would in turn be manifested by quantitative and qualitative changes in choroidal vessel structure and architecture. These initial changes will eventually stabilise and revert to baseline after a period of long-term remodelling and adaptation.
Through this imaging study, the investigators aim to opportunistically study and validate these progressive choroidal vasculature changes in the choroidal outflow circulation following scleral buckle (SB) surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 21 years and above
- •Ability to provide informed consent
- •First occurrence of a retinal detachment in one eye, deemed to require SB surgery with or without vitrectomy and/or cataract surgery.
- •Clinically normal fellow eye (no previous intraocular surgery except for cataract extraction with lens implant, intraocular laser or injection procedures).
排除标准
- •Affected eye undergoing vitreoretinal procedure other than an SB surgery with or without vitrectomy and/or cataract surgery.
- •Pregnant or nursing women
- •Persons who are unable to give informed consent
结局指标
主要结局
Post operative choroidal venous congestion
时间窗: 1 year
Proportion of eyes demonstrating progression in choroidal venous congestion at 1 year, defined by increased choroidal thickness, increase in number of quadrants with pachyvessels, or new vortex vein anastomosis on multimodal imaging.
次要结局
未报告次要终点
研究者
Gemmy Cheung Chui Ming
Professor
Singapore National Eye Centre