The influence of proline betaine in orange juice on homocysteine concentrations in healthy male Caucasians

Phase 3

Completed

• Conditions: Healthy volunteers; Other -

• Registration Number: ACTRN12606000501549
• Lead Sponsor: Canterbury Health Laboratories

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-12-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 8

Inclusion Criteria

Healthy Caucasian volunteers, with a normal fasting plasma homocysteine concentration.

Exclusion Criteria

Vitamin B12 or folate deficiency, chronic or acute illness requiring prescription medication, current or previous history of vascular or renal disease, and smokers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma homocysteine concentrations[At baseline and 20, 40, 60 90, 120, 180, 240, 300, 360 minutes and 24 hours post-treatment.]

Secondary Outcome Measures

Name	Time	Method
Plasma glycine betaine and proline betaine concentrations [At baseline and 20, 40, 60 90, 120, 180, 240, 300, 360 minutes and 24 hours post-treatment.];Urine glycine betaine and proline betaine concentrations[At baseline and 20, 40, 60 90, 120, 180, 240, 300, 360 and 24 hours post-treatment.]