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Exercise training in patients with COPD

Completed
Conditions
chronic bronchitis
emphysema
10024970
Registration Number
NL-OMON35203
Lead Sponsor
niversiteit Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

•patient has provided written informed consent;
•patient is diagnosed with COPD (FEV1 / FVC postbronchodilatoir < 70%);
•patient is clinically stable;
•patient has stopped smoking;
•patient has an indication for lung rehabilitation

Exclusion Criteria

•patient is hypoxic at rest (PaO2 < 55 mg Hg)
•patient has experienced exacerbations in the last 8 weeks before commencement of the study
•patient has problems adapting to the disease, requiring a more behavioural intervention (extended programme).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Primary outcome variable in the study is: time trial endurance performance test<br /><br>(sec). </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Other parameters that will be measured at rest are: FEV1 (L/sec), FVC (L),<br /><br>Quality of life (questionnaire), ADL (questionnaire).<br /><br>Parameters that will be measured during maximal exercise are Peak VE (L/min),<br /><br>Peak VO2 (L/min), Peak CO2 output (L/min), SaO2 (%) HR (beats/min), dyspnea<br /><br>(visual analog scale), f (breaths/min), peak power (W), energy expenditure<br /><br>(Joules).<br /><br>PAEE will be measured during 7 days of free living by combined sensing of<br /><br>acceleration and heart rate with Actiheart-monitors.</p><br>
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