Exercise training in patients with idiopathic Pulmonary Arterial Hypertensio
- Conditions
- High pressure in the bloodvessels of the lungs1003868610037454
- Registration Number
- NL-OMON30030
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
- Mean pulmonary artery pressure (mPAP) > 25 mmHg
- Stable on therapy for at least 3 months
- Idiopathic pulmonary arterial hypertension
Exclusion Criteria
- Presence of systemic inflammation
- Patients with pulmonary hypertension associated with collagen vascular disease, congenital heart disease, chronic thrombo-embolic pulmonary hypertension, pulmonary venous hypertension, left heart failure, hypoxemic lung disease
- Patients with musculoskeletal problems prohibiting maximal exercise performance
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Main study parameters:<br /><br>- Change in strength and endurance of the quadriceps muscles<br /><br>- Change in exercise tolerance<br /><br>- Change in biochemical and morphological characteristics of the quadriceps<br /><br>muscles </p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>