Effect of Aerobic Exercise Training in Obese Adults

Not Applicable

Completed

• Conditions: Obesity
• Interventions: Other: Aerobic exercise training; Other: Conventional therapy

• Registration Number: NCT05202535
• Lead Sponsor: Riphah International University

Brief Summary

To determine the effect of aerobic exercise training on arterial stiffness and hemodynamics in obese adults. Proper evidence on the effect of aerobic exercise training on both arterial stiffness and hemodynamics are sparsely present in obese adults whereas separate studies were done in mainly hypertensive and cardiovascular disease populations.

Detailed Description

Obese adults always have been trying to improve their quality of life by managing the complications associated with obesity like arterial stiffness and disturbed hemodynamics.

Study Timeline

• Study Start: 2021-11-15
• Study First Submitted: 2022-01-08
• Study First Submitted QC: 2022-01-08
• Study First Posted: 2022-01-21
• Primary Completion: 2022-03-15
• Study Completion: 2022-03-15
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-15
• Last Update Posted: 2022-09-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• Body mass index ≥28 kg/m²
• Able to do exercise

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Exclusion Criteria

• Involved in structured physical activity in last 6 months
• History of chronic systemic disease (cardiovascular, pulmonary, and metabolic disease)
• Continuous medication use.
• MSK or Neurological problems
• Pregnant females

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aerobic exercise training	Aerobic exercise training	hospital-based aerobic exercise training on treadmill/cycle ergometer with the intensity of 40-70% of HR max, for 15-30 mints for 8 weeks
Conventional therapy	Conventional therapy	Patient education and counseling with diet plan.Walking 3 days15min/day for 8 weeks

Primary Outcome Measures

Name	Time	Method
Hemodynamics	6 weeks	Factors that govern blood flow calculated through Rate Pressure Product.
Arterial Stiffness	6 weeks	Gradual fragmentation and loss of elastin fibers and accumulation of stiffer collagen fibers in the arterial wall. Calculated through Arterial stiffness index.

Trial Locations

Locations (1)

Polyclinic Hospital; 🇵🇰 Islamabad, Punjab, Pakistan