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Clinical Trials/NCT05202535
NCT05202535CompletedNot Applicable

Effect of Aerobic Exercise Training on Arterial Stiffness and Hemodynamics in Obese Adults.

Riphah International University2 sites in 1 country34 target enrollmentStarted: November 15, 2021Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
34
Locations
2
Primary Endpoint
Hemodynamics

Study Overview

Brief Summary

To determine the effect of aerobic exercise training on arterial stiffness and hemodynamics in obese adults. Proper evidence on the effect of aerobic exercise training on both arterial stiffness and hemodynamics are sparsely present in obese adults whereas separate studies were done in mainly hypertensive and cardiovascular disease populations.

Detailed Description

Obese adults always have been trying to improve their quality of life by managing the complications associated with obesity like arterial stiffness and disturbed hemodynamics.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
20 Years to 40 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Body mass index ≥28 kg/m²
  • Able to do exercise

Exclusion Criteria

  • Involved in structured physical activity in last 6 months
  • History of chronic systemic disease (cardiovascular, pulmonary, and metabolic disease)
  • Continuous medication use.
  • MSK or Neurological problems
  • Pregnant females

Outcomes

Primary Outcomes

Hemodynamics

Time Frame: 6 weeks

Factors that govern blood flow calculated through Rate Pressure Product.

Arterial Stiffness

Time Frame: 6 weeks

Gradual fragmentation and loss of elastin fibers and accumulation of stiffer collagen fibers in the arterial wall. Calculated through Arterial stiffness index.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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