A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
Overview
- Phase
- Not Applicable
- Intervention
- Motivational Interviewing
- Conditions
- Posttraumatic Stress Disorder
- Sponsor
- University of Washington
- Enrollment
- 40
- Primary Endpoint
- Change From Baseline PTSD Checklist Civilian (PCL-C) at 1 Month
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The goal of this pilot study is to develop and implement a larger scale, multi-site stepped collaborative care trial that targets injured patients with presentations of posttraumatic stress disorder (PTSD) and related comorbidities.
Investigators
Douglas Zatzick
Professor, Psychiatry & Behavioral Sciences
University of Washington
Eligibility Criteria
Inclusion Criteria
- •Inpatient/Emergency Admission for traumatic injury
Exclusion Criteria
- •Non-English speaking
- •Self-inflicted injury
- •Actively psychotic
- •Incarcerated or in custody
Arms & Interventions
Intervention
The intervention aims to prevent the development of chronic PTSD and depressive symptoms, alcohol use problems, and enduring physical disability in survivors of both TBI and non-TBI injuries. The intervention utilizes a computerized decision support tool to flexibly target these multiple conditions including and includes care management, medication, and psychotherapy elements.
Intervention: Motivational Interviewing
Intervention
The intervention aims to prevent the development of chronic PTSD and depressive symptoms, alcohol use problems, and enduring physical disability in survivors of both TBI and non-TBI injuries. The intervention utilizes a computerized decision support tool to flexibly target these multiple conditions including and includes care management, medication, and psychotherapy elements.
Intervention: Cognitive Behavioral Therapy Elements
Intervention
The intervention aims to prevent the development of chronic PTSD and depressive symptoms, alcohol use problems, and enduring physical disability in survivors of both TBI and non-TBI injuries. The intervention utilizes a computerized decision support tool to flexibly target these multiple conditions including and includes care management, medication, and psychotherapy elements.
Intervention: Psychotropic Drugs
Intervention
The intervention aims to prevent the development of chronic PTSD and depressive symptoms, alcohol use problems, and enduring physical disability in survivors of both TBI and non-TBI injuries. The intervention utilizes a computerized decision support tool to flexibly target these multiple conditions including and includes care management, medication, and psychotherapy elements.
Intervention: Care Management
Outcomes
Primary Outcomes
Change From Baseline PTSD Checklist Civilian (PCL-C) at 1 Month
Time Frame: Baseline and 1-month
The investigators will use the PTSD Checklist - Civilian (PCL-C). The scoring of the scale ranges from a minimum of 17 to a maximum of 85, with higher scores indicating a worse outcome. The measure can also provide a rating of symptoms consistent with a diagnosis of PTSD.
Change From Patient Health Questionnaire 9 Item Depression Scale at 1 Month
Time Frame: Baseline and 1-month
The investigators will use the Patient Health Questionnaire 9-item Depression Scale (PHQ-9). The scoring of the scale ranges from a minimum of 0 to a maximum of 27, with higher scores indicating a worse outcome.
Change From Baseline Alcohol Use Disorders Identification at 1 Month
Time Frame: Baseline and 1-month
The investigators will use the Alcohol Use Disorders Identification Test (AUDIT) as a continuous measure. The 10-item scale score ranges from 0-40, with higher values indicating a worse outcome.
Secondary Outcomes
- Change in Functional Status(Baseline and 1-month)
- Patient Health Questionnaire Item 9 Suicide Question(Baseline and 1-month)
- Number of Participants Endorsing a Single Item That Assesses Drug Use(Baseline and 1-month)
- Cognitive Impairment Scale(Baseline and 1-month)