Protein for Bone and mUScle health in hip fracture patients
- Conditions
- <p>Acute hip fracture</p>
- Registration Number
- NL-OMON22171
- Lead Sponsor
- Division of Human Nutrition and Health of Wageningen University & Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 102
?Age = 65 years
?Acute hip fracture
?Able to give written informed consent
?Admission to a rehabilitation centre that participates in this research
?Allergic, intolerant or hypersensitive to milk/lactose (self-reported)
?Not willing to stop using dietary supplements with exception of calcium and vitamin D
?Pathological fracture
?Abnormal hepatic or renal laboratory parameters, such as estimated glomerular filtration rate (eGFR) <30 ml/min/1,73 m2 (data from hospital)
?Diagnosis of disorders/diseases where a high protein intake can be harmful, such as renal impairment or failure, liver disease, or diabetes associated with nephropathy (geriatric care physician has the decisive voice).
?Diagnosis of bone metabolic disorders such as primary hyperparathyroidism, Paget’s disease, or myeloma
?Taking medication known to strongly alter bone or calcium metabolism, such as oestrogen, hormone replacement therapy, corticosteroids, anabolic agents, calcitonin, or bisphosphonates
?Disorders/diseases which may affect ability to follow study protocol and which cannot be overcome with help of a caregiver
?Current participation in other scientific research
? No permission to request information from the general practitioner/ treating specialist(s) about medical history, medication use, liver and kidney values, and details about the broken hip
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>? Markers of bone turnover: CTX and P1NP ? BMD: total hip, femoral neck, and total body ? IGF-1 levels ? Physical performance ? Muscle mass</p>
- Secondary Outcome Measures
Name Time Method <p>? Inpatient rehabilitation time ? Sarcopenia prevalence ? Daily life functioning ? Quality of life</p>