Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated with Antithrombotics for an Ischemic Stroke.

Recruiting

• Conditions: Stroke
• Interventions: Other: Analysis of the verbatim from the transcription of the recorded interviews.

• Registration Number: NCT05741593
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. There are brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.

Detailed Description

Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. The probability of stroke recurrence is high: about 25% the first year , and 30 to 40% in the 5 years following the stroke. Recurrent strokes are responsible for significant disability, institutionalization, major neurocognitive disorders, and death.

In order to reduce the risk of stroke recurrence, multiple secondary prevention strategies have demonstrated their effectiveness, such as the prescription of drugs (in particular statins and antithrombotics), the establishment of a balanced diet, the practice of an activity physical, or even tobacco addiction.

However, the effectiveness of these strategies is optimal if and only if patients adhere to them.

In addition, previous studies have focused on the brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.

In elderly patients, other obstacles could have been identified by specific studies, such as cognitive, sensory, functional disorders or even isolation.

Study Timeline

• Study First Submitted: 2023-02-14
• Study First Submitted QC: 2023-02-14
• Study First Posted: 2023-02-23
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-14
• Last Update Posted: 2024-11-18
• Study Start: 2025-04-01
• Primary Completion: 2026-04-01
• Study Completion: 2026-04-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients aged 65 and over
• Patients hospitalized for an ischemic stroke or a recurrence of ischemic stroke, already being treated with an antithrombotic treatment (antiplatelet agent or anticoagulant ) prior to the stroke
• Patients living at home and with a plan to return home.
• Patients who did not object to the study and who gave their consent for the recording of the interview

Exclusion Criteria

• Patients with cognitive disorders or stroke sequelae that do not allow a semi-directive interview to be carried out (at medical discretion).
• Non-French speaking patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients having had a stroke	Analysis of the verbatim from the transcription of the recorded interviews.	elderly patients previously treated with an antithrombotic and admitted to hospital for an ischemic stroke

Primary Outcome Measures

Name	Time	Method
Analysis of the verbatim from the transcription of the recorded interviews.	one year	Describing the content of discussions, relating to antithrombotic treatment for secondary prevention, between elderly patients previously treated with antithrombotics and admitted to hospital for an ischemic stroke and a pharmacist

Secondary Outcome Measures

Name	Time	Method
Analysis of verbatim statements from the transcription of recorded interviews on patients' representations and beliefs regarding antithrombotics	15 to 60 minutes per patient	Exploring patients' representations and beliefs regarding antithrombotics before and after the onset of stroke or recurrence of stroke
Analysis of verbatim statements from the transcription of recorded interviews on patients' medication adherence to antithrombotics	15 to 60 minutes per patient	Explore patients' medication adherence to antithrombotics before the onset of stroke or recurrence of stroke
Analysis of verbatim statements from the transcription of recorded interviews on the impact of the occurrence of stroke or recurrence of stroke on medication adherence	15 to 60 minutes per patient	Explore the impact of stroke occurrence or stroke recurrence on patient medication adherence (including motivation, ambivalence, confidence in medication benefits)
Analysis of verbatim statements from the transcription of recorded interviews on the obstacles and levers to medication adherence	15 to 60 minutes per patient	Identify the barriers and levers to drug adherence with antithrombotics

Trial Locations

Locations (1)

institute of aging - Hôpital des Charpennes; 🇫🇷 Villeurbanne, France