Quantifying biomarkers in patients with cleft lip/cleft palate undergoing fixed mechanotherapy
Not Applicable
- Conditions
- Health Condition 1: K088- Other specified disorders of teethand supporting structures
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with unilateral cleft lip and palate
12-18 years
Both sexes
Non syndromic
No other congenital abnormalities
No history of previous orthodontic treatment
Exclusion Criteria
Individuals having cleft lip and palate with any syndromes, congenital disorders.
Individuals with systemic diseases affecting bone density
Previous orthodontic intervention
Bilateral CLCP patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the miR-223 & Hmox expressed in salivary fluid in CL/CP patients and healthy patients during fixed mechanotherapy.Timepoint: Baseline: T0 <br/ ><br>7th day: T1 <br/ ><br>14Tth day: T2 <br/ ><br>30th day: T3 <br/ ><br>60th day: T4
- Secondary Outcome Measures
Name Time Method To compare these biomarkers at the end of the treatmentTimepoint: at the end of the treatment