Yoga Intervention for the Improvement of Cancer-Related Stress in Cancer Survivors

Not Applicable

Recruiting

• Conditions: Hematopoietic and Lymphoid Cell Neoplasm; Malignant Solid Neoplasm
• Interventions: Other: Quality-of-Life Assessment; Other: Survey Administration; Other: Yoga

• Registration Number: NCT04754529
• Lead Sponsor: Roswell Park Cancer Institute

Brief Summary

This clinical trial develops and test a yoga intervention in improving cancer-related stress in cancer survivors. The online hatha yoga intervention of breathing and movement incorporates both restorative poses, breathing techniques, guided meditation and may reduce stress levels and improve overall quality of health in cancer survivors.

Detailed Description

PRIMARY OBJECTIVE:

I. To develop and test the feasibility of a standardized 12-week online hatha yoga intervention (n=30) of breathing and movement incorporating both restorative poses, breathing techniques, guided meditation.

SECONDARY OBJECTIVES:

I. To evaluate the yoga intervention in relation to self-reported levels of stress and quality of life in cancer survivors (n=30).

II. Feasibility of collecting blood and saliva at baseline and post-intervention for stress biomarkers, including cortisol and norepinephrine.

EXPLORATORY OBJECTIVE:

I. To determine how behavior change, quality of life (QoL), and biomarkers of adrenergic stress, inflammation, and immunosuppression are affected by a 12-week online yoga program completed by cancer survivors.

OUTLINE:

Patients receive online yoga intervention once a week (QW) for 12 weeks.

After completion of study, patients are followed up at 3 months.

Study Timeline

• Study First Submitted: 2021-02-08
• Study First Submitted QC: 2021-02-11
• Study First Posted: 2021-02-15
• Study Start: 2021-11-11
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-01
• Last Update Posted: 2025-04-02
• Primary Completion: 2025-05-15
• Study Completion: 2025-05-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Age >= 18 years of age
• Have been diagnosed with a cancer and have finished treatment
• Have been cleared for physical activity by a physician or nurse practitioner (physician or nurse practitioner name and date clearance received)
• Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure

Exclusion Criteria

• Unwilling or unable to complete the assessment in English
• Are pregnant or nursing
• Are unwilling or unable to follow protocol requirements
• Have skeletal instabilities and/or cardio-pulmonary comorbidities
• Have any condition which in the investigator's opinion deems the subject an unsuitable candidate to participate in this study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Supportive care (yoga)	Quality-of-Life Assessment	Patients receive online yoga intervention QW for 12 weeks.
Supportive care (yoga)	Survey Administration	Patients receive online yoga intervention QW for 12 weeks.
Supportive care (yoga)	Yoga	Patients receive online yoga intervention QW for 12 weeks.

Primary Outcome Measures

Name	Time	Method
Proportion of subjects who participate or show high adherence to the intervention	Up to 12 weeks	Will be presented as observed proportion and 95% Clopper-Pearson confidence intervals (CIs).

Secondary Outcome Measures

Name	Time	Method
Efficacy of the intervention in stress-reduction	Up to 3 months post intervention	Self report stress
Efficacy of the intervention in stress reduction	Up to 3 months post intervention	salivary cortisol will be measured by saliva collection

Trial Locations

Locations (1)

Roswell Park Cancer Institute; 🇺🇸 Buffalo, New York, United States