Effect of test food consumption on tear secretion and physical condition.
- Conditions
- Healthy adults
- Registration Number
- JPRN-UMIN000029577
- Lead Sponsor
- Kyodo Milk Industry Co. Ltd. Research Laboratories
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Not provided
1. Subjects under treatment of eyes 2. Subjects who operated or plan an operation for eyes within three months of screening test 3. Subjects who have serious or progressive illness and symptom 4. Subjects who routinely take pharmaceutical, quasi drug or health food, which may influence the result of this trial (including foods containing oligosaccharide, dietary fiber, hydrogen water and supplements that produce hydrogen gas) 5. Subjects who can avoid the intake of milk and dairy products except test food from screening examination to three weeks later 6. Subjects who have food allergies or drug allergies 7. Subjects with serious lactose intolerance (diarrhea) 8. Subjects who have serious constipation which need to take cathartic drugs and laxative products 9. Subjects under treatment of dry eye 10. Subjects who were enrolled in other trails within one month of screening test 11. Female Subjects who are or might become pregnant 12. Subjects who have history of serious hepatic disorder, renal damage, or myocardial infarction 13. Subjects who have been receiving drug treatment 14. Subjects with severe anemia 15. Inappropriate cases evaluated by doctors
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BUT, Schirmer's test, Questionnaire about ocular symptoms
- Secondary Outcome Measures
Name Time Method Fecal microbiota, breath hydrogen concentration, oxidative-stress marker in tear, and questionnaire