The Influence of the Pre-operative Nociceptive Profile on the Development of Chronic Pain after Inguinal Hernia Repair Surgery

Completed

• Conditions: Pijngeneeskunde; chronic pain; neuropathic pain

• Registration Number: NL-OMON44933
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-01-30
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 250

Inclusion Criteria

- American Society of Anesthesiologists score 1, 2 or 3
- aged 18 to 75 years
- planned to undergo elective surgery involving an inguinal hernia repair

Exclusion Criteria

(1) Pain scores > 3 (on a 11-point numerical rating scale, NRS) reported for most of the day during the past month;
(2) Regular use of analgesics for any purpose, including SNRIs, gabapentinoids, COX inhibitors or NSAIDs during the previous month;
(3) The presence of any chronic pain disorder;
(4) Inability to perform psychophysical testing (eg. in case of cognitive or psychiatric disorders);
(5) Inability to give informed consent;
(6) Inability to communicate with the investigators;

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- endogenous pain modulation: pro-nociceptive profile vs anti-nociceptive<br /><br>profile<br /><br>- development of chronic pain</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Acute pain and analgesic use in the first 24 hours after surgery</p><br>