Early Diagnosis of Acute Renal Failure by Urine Trehalase Levels.

Not yet recruiting

• Conditions: Trehalase Levels; Acute Kidney Injury

• Registration Number: NCT06505655
• Lead Sponsor: Istinye University

Brief Summary

We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method, and thus, early diagnosed acute renal failure can be treated quickly and patients can be protected from subsequent complications in the postoperative period.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2024-07
• Study First Submitted: 2024-07-11
• Study First Submitted QC: 2024-07-11
• Last Update Submitted: 2024-07-11
• Study Start: 2024-07-15
• Study First Posted: 2024-07-17
• Last Update Posted: 2024-07-17
• Primary Completion: 2024-08-15
• Study Completion: 2024-09-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Being over the age of 18 and under the age of 65
• Having signed the BGOF form to be included in the study,
• Being in ASA 1 or ASA 2 classification
• Not having kidney failure or kidney disease
• No history of single kidney or renal transplantation
• Not using nephrotoxic drugs or agents before surgery
• Renal function tests taken preoperatively should be within normal ranges.
• No urinary tract infection or urinary problems (such as polyuria, oliguria or anuria)

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Exclusion Criteria

• Those under the age of 18 or over the age of 65
• Those who do not want to participate in the study
• ASA 3 and above
• Having previously received treatment for kidney disease - including kidney stones -
• Having been previously diagnosed with acute or chronic renal failure
• Having a single kidney or a history of renal transplantation
• Using nephrotoxic drugs or agents (such as contrast material) before surgery
• Kidney function tests taken preoperatively are not within normal ranges
• Having a urinary tract infection or urinary problem (such as polyuria, oliguria or anuria)
• Having a history of kidney stones, acute renal failure or chronic renal failure
• Those with active infection or disease before surgery
• They were determined as patients for whom consent was not obtained for the study.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
trehalase levels	1 month	urine trehalase levels

Trial Locations

Locations (1)

Istinye Üniversity; 🇹🇷 Istanbul, Merkez Mahallesi, Turkey