Mixed Venous Oxygen Saturation From Central Venous Line, Venous Side of Heart Lung Machine and the Pulmonary Artery

Completed

• Conditions: Heart Defects, Congenital
• Interventions: Other: venous saturations

• Registration Number: NCT02498626
• Lead Sponsor: Assiut University

Brief Summary

This study was designed to examine if venous saturations from the central venous line and from the venous side of the heart lung machine are interchangeable or not with mixed venous saturation from the pulmonary artery in children undergoing open heart surgery for correction of various congenital heart defects.

Detailed Description

Forty children aged from 1-15 years undergoing correction for different congenital heart procedures with cardiopulmonary bypass \[CPB\] were included in this study. Simultaneous samples were taken from the central venous line, pulmonary artery, and from venous side of the heart lung machine. Samples were taken after 10 minutes on full CPB and at the end of surgery before end of CPB. Bland and Altman plots were used to study the agreement between venous saturations.

Study Timeline

• Study Start: 2009-07
• Study First Submitted: 2015-06-24
• Study First Submitted QC: 2015-07-14
• Study First Posted: 2015-07-15
• Primary Completion: 2016-01
• Study Completion: 2016-01
• Status Verified: 2016-02
• Last Update Submitted: 2016-05-07
• Last Update Posted: 2016-05-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Children in the age from 1-15 years undergoing correction for congenital heart defects with cardiopulmonary bypass

Exclusion Criteria

• Any chest renal or hepatic problems

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
venous saturations	venous saturations	venous saturations from the central venous line, venous side of the heart lung machine and from the pulmonary artery

Primary Outcome Measures

Name	Time	Method
Bland and Altman Analysis was used to plot the difference in mixed oxygen saturation	intraoperative	The agreement between these samples from the central venous line, venous side of the heart lung machine and from the pulmonary artery were done using bland and Altman Analysis

Trial Locations

Locations (1)

Faculty of Medicine; 🇪🇬 Assiut, Egypt