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To Understand the relationship between PCO2 gap, calculated respiratory quotient and serum lactate in patients with septic shock.

Not Applicable
Conditions
Health Condition 1: O- Medical and Surgical
Registration Number
CTRI/2023/10/058869
Lead Sponsor
DANISH AHMAD
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

PATIENTS ADMITTED WITH SEPTIC SHOCK

Exclusion Criteria

-Patients with all types of Shock other than Septic Shock.

- Trauma Patients.

- Pregnant Patients.

- ARDS, COPD Patients.

- Seizure Disorder patients.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate correlation between Pv-aCO2, PcvCO2– PaCO2/CaO2–CcvO2 ratio and the arterial lactate at various time points till 24 hours, in management of patients with septic shock. <br/ ><br>Timepoint: To evaluate correlation between Pv-aCO2, PcvCO2– PaCO2/CaO2–CcvO2 ratio and the arterial lactate at various time points 0,6 ,12, 24 hours, in management of patients with septic shock. <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
1. To ascertain whether the Pv-aCO2, PcvCO2–PaCO2/CaO2–CcvO2 ratio and the arterial lactate levels in the first 24 hours are able to predict outcome of the patient in terms of: - <br/ ><br>a. Organ dysfunction at 48 hours, as assessed by (SOFA) score <br/ ><br>b. Vasopressor free days. <br/ ><br>c. Length of stay in ICU. <br/ ><br>d. Mortality within 28 days. <br/ ><br> <br/ ><br>Timepoint: 28 days.;To determine whether the Pv-aCO2, PcvCO2–PaCO2/ CaO2–CcvO2 ratio and arterial lactate are useful in discriminating survivors from non-survivors.Timepoint: Survivor from non survivor
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