ACTRN12620000243910
Recruiting
未知
Is skeletal muscle microvascular dysfunction a key determinant of exercise intolerance and impaired glycaemic control in patients with type 2 diabetes?
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Metabolic and endocrine
- Sponsor
- Deakin University
- Enrollment
- 56
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Aged 40–80 years.
- •2\.Clinical diagnosis of pre\-diabetes (HbA1C \= 5\.7%) or T2D (HbA1C \= 6\.5%)
- •Controlled diabetes through diet or medication (excluding insulin) for at least 8 weeks.
- •3\.Have given signed informed consent to participate in the study.
Exclusion Criteria
- •1\.Age \<40 years or \> 80 years.
- •2\.Patients using insulin to control blood sugar levels.
- •3\.Pulmonary hypertension.
- •4\.Atrial fibrillation.
- •5\.Cardiovascular disease including coronary artery disease or heart valve disease.
- •6\.Poor ejection fraction (\<50%) or elevated left ventricle filling pressure (E/e’ \>15\).
- •7\.Critical limb ischemia including peripheral artery disease or previous revascularisation or other surgical treatment for peripheral artery disease.
- •8\.History of malignancy within past 5 years (except for non\-melanoma skin cancers).
- •9\.Identification of any medical condition requiring immediate therapeutic intervention.
- •10\.Uncontrolled hypertension (resting brachial blood pressure greater than or equal to 160/100 mmHg).
Outcomes
Primary Outcomes
Not specified
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