Effect of home-based exercise training on muscle microvascular dysfunction in type 2 diabetes.
- Conditions
- Metabolic and endocrineMetabolic and Endocrine - DiabetesPhysical Medicine / Rehabilitation - Other physical medicine / rehabilitation
- Registration Number
- ACTRN12620000243910
- Lead Sponsor
- Deakin University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 56
1.Aged 40–80 years.
2.Clinical diagnosis of pre-diabetes (HbA1C = 5.7%) or T2D (HbA1C = 6.5%)
Controlled diabetes through diet or medication (excluding insulin) for at least 8 weeks.
3.Have given signed informed consent to participate in the study.
1.Age <40 years or > 80 years.
2.Patients using insulin to control blood sugar levels.
3.Pulmonary hypertension.
4.Atrial fibrillation.
5.Cardiovascular disease including coronary artery disease or heart valve disease.
6.Poor ejection fraction (<50%) or elevated left ventricle filling pressure (E/e’ >15).
7.Critical limb ischemia including peripheral artery disease or previous revascularisation or other surgical treatment for peripheral artery disease.
8.History of malignancy within past 5 years (except for non-melanoma skin cancers).
9.Identification of any medical condition requiring immediate therapeutic intervention.
10.Uncontrolled hypertension (resting brachial blood pressure greater than or equal to 160/100 mmHg).
11.Other non-cardiovascular barriers to exercise
12.Current or previous smoker with past 12 months.
13.Participation or intention to participate in a structured and/or supervised physical activity program during the study period.
14.History of severe liver disease.
15.Elective major surgery during the course of the study.
16.Pregnancy/lactation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method