Evaluation of EUS-guided alcohol ablation effectiveness in treatment of insolinoma

Phase 1

• Conditions: insulinoma.; Pancreas, unspecified

• Registration Number: IRCT201201098635N2
• Lead Sponsor: Research Deputy of Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

•Biochemically proven solitary insulinoma
•Ages between 18 and 80 years old
Exclusion criteria:
•Insulinoma size of 2 cm or more
•Presence of lymph node, or vascular involvement of the tumor in EUS or spiral CT scan
•Presence of liver or other distant metastases in the spiral CT scan
•Presence of MEN-1 syndrome
•Presence of multiple insulinomas
•Inability to localize the tumor by EUS
•Unwilling to assign inform consent

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effectivenrss of the process. Timepoint: In the first and third month after treatment, BS level, and also in the third month the size of tumor would be measured and regiter by (EUS) method. Method of measurement: According to check list.;Serum amylase. Timepoint: 12, 24 and48 hours post(EUS). Method of measurement: Patients blood sampling.;Serum lipase. Timepoint: 12, 24 and 48 hours post(EUS). Method of measurement: Patient's blood sampling.;The procedure's time. Timepoint: During sonography and alcohol injection. Method of measurement: According to endoscopist's report.

Secondary Outcome Measures

Name	Time	Method
Complications. Timepoint: During first 48 hours of admission. Method of measurement: According to physical exams and tests.;Admission time. Timepoint: The average of the patient's spending days while the procedure untill discharging from the hospital. Method of measurement: According to the file.