Reduction of the Duration of Antibiotic Guided by Procalcitonin in Infections Lungs of Hospitalized Elderly: a Randomized

University Hospital, Grenoble1 site in 1 country117 target enrollmentAugust 2012

ConditionsLung Infection

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Lung Infection
Sponsor: University Hospital, Grenoble
Enrollment: 117
Locations: 1
Primary Endpoint: Duration of antibiotic therapy
Status: Terminated
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The main objective is to evaluate the interest of the repeated measurement of procalcitonin in patients with pulmonary infection to reduce the duration of antibiotic therapy in comparison with a conventional clinical strategy.

Registry

clinicaltrials.gov

Start Date

August 2012

End Date

March 2016

Last Updated

4 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University Hospital, Grenoble

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age ≥ 80 years
•Started antibiotics for a chest infection
•Procalcitonin performed J0 antibiotic treatment
•Person affiliated to the social security

Exclusion Criteria

•Patients with a documented infection with germs after Listeria spp, Legionella pneumophilia, Mycobacterium tuberculosis
•Patients with a documented infection with a virus or parasite (eg hemorrhagic fever, malaria)
•Patients with endovascular infection associated (endocarditis, pacemaker. Intravascular catheter)
•Patients with lung abscess associated upon entry Patients with a chronic infection associated
•Patients with severe immunosuppression (HIV or transplant)
•Palliative patient
•Death within 24 hours of admission to nursing units.
•Presence of antibiotic treatment for chronic infection.
•Patient under guardianship, curatorship or any other administrative or judicial action or deprivation of the right or freedom
•Patients hospitalized without their consent