Comparison between extension of specialised early intervention for first episode psychosis and regular care: a randomised controlled trial

Not Applicable

Completed

• Conditions: First episode psychosis; Mental and Behavioural Disorders; Unspecified nonorganic psychosis

• Registration Number: ISRCTN11889976
• Lead Sponsor: Douglas Hospital Research Centre (Canada)

Brief Summary

2015 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/25784411 2020 results in https://pubmed.ncbi.nlm.nih.gov/30963544/ (added 06/07/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-06-10
• Study Completion: 2014-04-01
• Last Update Posted: 20 July 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 217

Inclusion Criteria

The aim of our study is to demonstrate effectiveness of a model of care applicable to the largest number of persons with first episode psychosis (FEP) as they appear in clinical settings and not to show efficacy of a single treatment intervention for patients with pure unencumbered diagnoses. Therefore, the inclusion criteria are designed to recruit patients truly representative of FEP patients likely to be seen in any treatment facility:
1. Aged 18 - 35 years, either sex
2. Able to provide informed consent
3. Meeting Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) criteria for a psychotic disorder (schizophrenia spectrum psychoses and affective psychosis) confirmed by the Structured Clinical Interview for DSM-IV Axis I disorders Patient Edition
4. Have completed 24 months of treatment and follow-up in one of the two SEI services. Patients with co-morbid diagnosis of substance abuse and dependence will be included.

Exclusion Criteria

1. Lack of ability to provide informed consent as assessed by requesting patient to provide brief summary of treatment protocol following presentation of the consent form
2. Lack of ability to speak either English or French fluently as assessed by the patient indicating English or French as the preferred language for communication
3. Intelligence quotient (I.Q.) below 70 as assessed using the Wechsler Adult Intelligence Scale (WAIS) short form

Study & Design

• Study Type: Interventional
• Study Design: Not specified