Efficacy of USG guided genicular nerve block with aqueous phenol(6%),ethyl alcohol(95%) and triamcinolone(20mg)with lignocaine(2%)-a randomized controlled trial.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- General Objective is to evaluate reduction of pain in VAS Scale in grade III and grade IV osteoarthritis Knee as per KL grading
研究概览
简要总结
Osteoarthritis knee (OA knee) causes significant pain and disability in the aged population. Increasing trend in prevalence data of OA Knee in the Indian subcontinent needs urgent, specific management protocol to reduce the morbidity of the patient, caregivers’ burden, and socio-economic burden. With increasing grading of OA knee; there is increasing chances of disability, decreasing pain control, increasing pill burden of patients, and increasing medication related side effects also and many of them don’t want to undergo for surgery or otherwise contraindicated for surgical intervention. The present study aims to describe the role of genicular nerve block by 6% aqueous phenol, 95% ethyl alcohol and triamcinolone 20 mg with 2% lignocaine, under USG guidance in treatment of Grade III and Grade IV OA knee. As there are scarcity of evidences of newer methods of treatment, its practical implications, and head to head study of newer agents are also lacking; hence this is our humble approach.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients from out patient department during the study primary osteoarthritis knee age between 40 to 60 years both gender clinically and radiologically confirmed for at least 3 months of duration.
排除标准
- •Patients with secondary osteoarthritis knee grade I and II osteoarthritis knee KL grading patients with uncontrolled comorbidities patients who got intraarticular injection in knee joint within last 3 months patients of syndrome complex not willing to give consent with psychiatric disorder of malignancy of bleeding diathesis with history of allergy of any of the pharmacological agents with infection either systemic or local history of knee surgery with anticoagulant medications.
结局指标
主要结局
General Objective is to evaluate reduction of pain in VAS Scale in grade III and grade IV osteoarthritis Knee as per KL grading
时间窗: outcome will be assessed at baseline or 0 week 4th week 12th week and at 24th week
Specific Objectives are to assess the improvement in knee pain and quality of life in KOOS Scale to find out the improvement in the sleep quality in Pittsburgh sleep quality index PSQI scale to identify the side effects if any due to intervention
时间窗: outcome will be assessed at baseline or 0 week 4th week 12th week and at 24th week
次要结局
- To assess the improvement in knee pain quality of life in KOOS Scale to find out the improvement in sleep quality in Pittsburgh sleep quality index PSQI scale to identify the side effects if any due to intervention(Outcome will be assessed at baseline or 0 week 4th week 12th week 24th week)
研究者
NIBEDITA MALIK
Nil Ratan Sircar Medical College and Hospital