PREDICTIVE MODELS FOR RADIATION-INDUCED SIDE EFFECTS IN HEAD AND NECK CANCER BASED ON SINGLE NUCLEOTIDE POLYMORPHISMS (SNP)

Recruiting

• Conditions: Toxiciteit radiotherapie in hoofd-halskanker patiënten; normal tissue toxicity; radiation toxicity; 10027656

• Registration Number: NL-OMON50431
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 2000

Inclusion Criteria

1. Histological proven head and neck cancer;
2. Primary site in the oral cavity, oropharynx, hypopharynx, nasopharynx,
paranasal sinuses, and/or salivary glands;
3. Treatment with curative intent with primary or postoperative radiotherapy
either or not combined with systemic treatment;
4. Northern European ethnicity (ethnicity is a known confounder in SNP
association studies);
5. Willing and able to comply with the study prescriptions;
6. 18 years or older;
7. No prior radiation (in the head and neck area);
8. Patients must have sufficient knowledge of the Dutch language to understand
the meaning of the study as described in the patient information;
9. Have given written informed consent before patient registration.

Exclusion Criteria

Prior radiotherapy.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified