Comparison of anesthetic drugs to create deep sedation.
Phase 2
- Conditions
- Procedural Sedation and Analgesia.
- Registration Number
- IRCT2015112525235N1
- Lead Sponsor
- Vice Chancellor for Reseach of Shahid Beheshti University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 122
Inclusion Criteria
Patients admitted to the emergency department of Emam Hossein hospital over 15 years to 60 years of age and they need Procedural sedation and analgesia (PSA)
Exclusion criteria: previous allergy to drugs used in the study; sensitivity to egg or soy products; Hemodynamic Instability; pregnancy; drug interactions; increased intracranial pressure (ICP)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The needed time for recovery from deep sedation. Timepoint: Every 30 seconds since the beginning of deep sedation. Method of measurement: The interval time between induction of sedation (Ramsay score 6) and recovery (Ramsy score of 2.;The depth of sedation. Timepoint: Every 30 seconds since the beginning of sedation. Method of measurement: the depth of sedation according to the Ramsay score.;The time required to create deep sedation. Timepoint: Every 30 seconds. Method of measurement: Since the beginning of sedative drugs to achieve deep sedation (Ramsay score equal to 6).
- Secondary Outcome Measures
Name Time Method Cardiac arrhythmia. Timepoint: continuously since the beginning of sedation. Method of measurement: Cardiac monitoring.;Arterial blood pressure. Timepoint: Before prescription of drugs, then every 5 minutes until recovery time. Method of measurement: Using the sphygmomanometer.;Physician and patient's satisfaction. Timepoint: after the procedure. Method of measurement: By questionnaire.;Arterial blood oxygen saturation. Timepoint: Continuously since the beginning of sedation. Method of measurement: Pulse oximetry.;Vomiting. Timepoint: since the beginning of sedation until full recovery. Method of measurement: Observation.