Retrospective Observation of Outcomes of Embryos Transferred After Initial Chaotic Results on Preimplantation Genetic Testing for Aneuploidy (PGT-A)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- Embryo transfer rate
研究概览
简要总结
This is a retrospective review of treatment outcomes from fertility clinics in The Prelude Network who have used Igenomix for PGT-A and have transferred embryos with initial chaotic results, regardless if re-biopsy was performed.
详细描述
Primary objective: to observe the outcomes of embryos transferred with initial "chaotic" results on PGT-A via Igenomix.
Hypothesis
The transfer of chaotic embryos can result in clinical pregnancy, as defined by fetal heartbeat at 6-8 weeks gestation. Furthermore, these transfers may also result in live birth and expand reproductive potential for patients seeking IVF with PGT-A.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients that conducted PGT-A via Igenomix who have transferred an embryo with an initial chaotic result.
排除标准
- •Patients who had multiple embryo transfer.
结局指标
主要结局
Embryo transfer rate
时间窗: 2 years
Frequency of embryo transfer post re-biopsy
Live birth rate
时间窗: 2 years
Frequency of live birth post embryo transfer of initial chaotic embryo
Pregnancy rate
时间窗: 2 years
Frequency of positive serum pregnancy test post embryo transfer of initial chaotic embryo
Embryo re-biopsy rate
时间窗: 2 years
Frequency of re-biopsy post initial chaotic PGT-A result
次要结局
未报告次要终点