Neural Bases of Multiple Forms of Self-regulatory Control in Bulimia Nervosa
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 89
- 试验地点
- 1
- 主要终点
- Self-Regulatory Control
研究概览
简要总结
The purpose of this study is to investigate areas of the brain responsible for self-regulation in adult women who have never had an eating disorder with women who have bulimia nervosa. More specifically, investigators are interested in changes in brain activation (e.g., changes in blood flow and oxygen use) when inhibiting responses and regulating emotions. Data collection will rely on a technology called functional magnetic resonance imaging (fMRI).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Right-handed
- •Between the ages of 18 and 35 years
- •*For Women with Bulimia Nervosa:
- •Binge eating (i.e., eating a large amount of food while experiencing a sense of loss of control)
- •Purging via self-induced vomiting (other methods may also be endorsed)
排除标准
- •Current significant medical illness or condition (e.g., diabetes, thyroid disease)
- •Pregnancy, planned pregnancy, or lactation during the study period
- •Non-removable metallic objects in the body
结局指标
主要结局
Self-Regulatory Control
时间窗: Day 2 (fMRI Scan)
Functional Magnetic Resonance Imaging will be used to assess brain activation associated with motor inhibitory control and affect regulation in women with bulimia nervosa (BN)
次要结局
- Eating Disorder Relevance(Day 0)
- Goal-Directed Action Control(Day 1)
研究者
Walter Kaye
Principal Investigator
University of California, San Diego
