To compare the effect of IM inj 10U oxytocin V/s Oral tablet Misoprostol in active management of third stage of labour
Phase 3
- Conditions
- Health Condition 1: O721- Other immediate postpartum hemorrhage
- Registration Number
- CTRI/2024/07/070533
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Women with gestational age more than 28 weeks and at low risk , undergoing vaginal delivery.
2. Patients having the ability and willingness to provide an informed consent.
Exclusion Criteria
1. Hb under 8gm
2. Previous pregnancy associated with PPH.
3. Patient with traumatic PPH due to genital laceration.
4. Antepartum haemorrhage.
5. Multiple pregnancies.
6. Non-cephalic presentation.
7. Multipara, big baby, fibroid uterus, polyhydramnios
8. Previous LSCS
9. Hypertension, pre-eclampsia or pregnancy induced hypertension.
10. Intra uterine death.
11. Seizures, diabetes, renal anomalies, cardiac arrest or coagulation disorders.
12. Choriamnionitis
13. Polyhydraminos.
14. Epidural anaesthesia.
15. Bronchial asthma or respiratory disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To measure the blood loss in the third stage of labour by changes in the level of haemoglobin and haematocrit after comparing these in both pre-delivery and on day 2 post-delivery of two intervention groups. <br/ ><br>2. To assess need of additional uterotonics or surgical methods for the control of postpartum haemorrhage <br/ ><br>Timepoint: 1. To measure the blood loss in the third stage of labour by changes in the level of haemoglobin and haematocrit after comparing these in both pre-delivery-baseline and post-delivery at day 2 and on discharge of two intervention groups. <br/ ><br>2. To assess need of additional uterotonics or surgical methods for the control of postpartum haemorrhage post delivery <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.To ascertain the side effects of the IM oxytocin & oral misoprostol <br/ ><br>2. Need of blood transfusion <br/ ><br>Timepoint: To be decided at the time of discharge on day 2 after delivery of baby