Comparison of the effectiveness of chewing gum with and without Ginger officale on dry mouth condition in patients under hemodialysis

Phase 3

• Conditions: Xerostomia.; Disturbances of salivary secretion; K11.7

• Registration Number: IRCT20201201049550N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

People of both sexes over 18 years old
Confirmation of dry mouth, regardless of the cause, by the standard dry mouth questionnaire, which includes questions related to the amount of saliva in the mouth, swallowing difficulty, a feeling of dryness while eating, the need to drink water while eating, will be examined.

Exclusion Criteria

Patients who are unable to chew gum due to oral conditions
History of allergic reaction to chewing gum and its contents , including ginger
Severe cognitive deterioration
Effective conditions on salivary flow rate : salivary gland aplasia , severe dehydration , chemotherapy , radiation to the head and neck and medications includes : ( Tricyclics Anti Deppressants - Tranquiliser - Sedative - Anticoagulants - Antihistamines - Antihypertensive drugs - Antispasmodic and diuretics ) - Sjogren's syndrome - Diabetes Mellitus - Sarcoidosis - Human immuno deficiency virus - Hepatitis C - Graft versus Host Disease (GvHD) - Mental Disorders - Primary biliary Cirrhosis - Systemic lupus erythematosus - Rheumatoid arthritis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Stimulated saliva level. Timepoint: Measurement of stimulated saliva and non-stimulating saliva before the intervention and 14 days after chewing gum. Method of measurement: Measurement of stimulated saliva in milliliters in a plastic vial.

Secondary Outcome Measures

Name	Time	Method
nstimulated saliva. Timepoint: Measurement of non-stimulating saliva before the intervention and 14 days after begining the intervention. Method of measurement: Measurement of non-stimulating saliva in milliliters in a plastic vial.;Oral health related quality of life. Timepoint: Before the intervention and 14 days after the intervention. Method of measurement: Oral Health Impact Profile-14 ( OHIP-Per14 ) questionnaire.;Severity of dry mouth. Timepoint: Before the intervention and 14 days after the intervention. Method of measurement: Xerostomia Inventory (XI) questionnaire (11 questions).