Comparison of two vitamin D dosing regimens for osteoprotection in children with new-onset and infrequently relapsing nephrotic syndrome treated with steroids : a randomized trial.

JIPMER Intramural fund0 个研究点目标入组 90 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Inclusion criteria :
•Children with new- onset and infrequently relapsing nephrotic syndrome receiving steroids, attending pediatric nephrology clinic and pediatric wards, JIPMER

•Exclusion criteria :
•i)Children with history of hypocalcemic seizure, tetany, rickets or fractures.
•ii)Known cases of renal stones.
•iii)Children with NS already on calcium and vitamin D supplements.
•iv)Sexual maturity rating (SMR grade 2, by Tanner staging) and above.
•v)Frequently relapsing, steroid dependent and steroid resistant NS.
•vi)Children on cyclosporine therapy, phenytoin, phenobarbitone, methotrexate or requiring any immunosuppressant other than prednisolone.
•vii)Chronic renal failure or chronic liver disease.
•viii)Secondary causes of NS (e. g IgA nephropathy, Henoch Schonlein Purpura nephritis ,Lupus nephritis)

发起方

JIPMER Intramural fund