Comparison of two different vitamin D doses for bone strength protection in nephrotic syndrome

Phase 2

• Conditions: Health Condition 1: null- New-onset,Infrequently relapsing nephrotic syndrome

• Registration Number: CTRI/2015/04/005721
• Lead Sponsor: JIPMER Intramural fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

Inclusion criteria :

Children with new- onset and infrequently relapsing nephrotic syndrome receiving steroids, attending pediatric nephrology clinic and pediatric wards, JIPMER

Exclusion Criteria

Exclusion criteria :

i)Children with history of hypocalcemic seizure, tetany, rickets or fractures.

ii)Known cases of renal stones.

iii)Children with NS already on calcium and vitamin D supplements.

iv)Sexual maturity rating (SMR grade 2, by Tanner staging) and above.

v)Frequently relapsing, steroid dependent and steroid resistant NS.

vi)Children on cyclosporine therapy, phenytoin, phenobarbitone, methotrexate or requiring any immunosuppressant other than prednisolone.

vii)Chronic renal failure or chronic liver disease.

viii)Secondary causes of NS (e. g IgA nephropathy, Henoch Schonlein Purpura nephritis ,Lupus nephritis)

Study & Design

• Study Type: Interventional
• Study Design: Not specified