The effect of Dexmedetomidine on recovery after General Anaesthesia- a randomized controlled study
Phase 4
Completed
- Conditions
- Health Condition 1: null- Patients undergoing elective surgery under general anaesthesia of expected duration less than 2 hours
- Registration Number
- CTRI/2018/03/012327
- Lead Sponsor
- Jawaharlal Institute of Postgraduate Medical Education Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
ASA 1 & 2 patients undergoing elective surgery of expected duration less than 2 hrs under general anaesthesia
Exclusion Criteria
Patients refusing consent, known history of psychiatric illness, chronic drug or alcohol abuse, known hypersensitivity to drugs used, family history of malignant hyperthermia, significant cardiopulmonary, hepatic or renal disease, pregnant and breast feeding women, hypertensive patients not on any treatment or those treated with alpha or beta blockers and patients on concurrent sedative medications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Psychomotor function was assessed by Trieger dot test (TDT) and Digit symbol substitution test (DSST).Timepoint: Both the tests were done pre-operatively (baseline), 30 minutes, 60 minutes, 90 minutes and 120 minutes after extubation.
- Secondary Outcome Measures
Name Time Method Total opioid requirementTimepoint: Fentanyl 1 µg/kg was supplemented whenever there was increase in patients heart rate or blood pressure by 30% from baseline in both the groups during surgery