Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema

Phase 4

Completed

• Conditions: Edema; Trismus; Infection, Surgical Site; Pain
• Interventions: Drug: Hyaluronidase Injection mesomedica; Drug: Dexamethasone dekort

• Registration Number: NCT05466604
• Lead Sponsor: Hacettepe University

Brief Summary

The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection. For this purpose, 60 participants with symmetrical mandibular wisdom teeth enrolled the present study. All measurements and evaluations were performed before and 1, 2, 3, and 7 days later the operation.

Detailed Description

Not available

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Study Start: 2019-12-01
• Primary Completion: 2022-06-30
• Study Completion: 2022-06-30
• Status Verified: 2022-07
• Study First Submitted: 2022-07-13
• Study First Submitted QC: 2022-07-15
• Last Update Submitted: 2022-07-15
• Study First Posted: 2022-07-20
• Last Update Posted: 2022-07-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• symmetrical mandibular wisdom teeth with bone retention
• patients who are signed informed consent and acceptance of study involvement forms

Read More

Exclusion Criteria

• existence of any systemic disease
• existence of any periodical drug intake
• existence of difference in operation times of right and left impacted wisdom teeth extractions more than 5 minutes
• existence of pregnancy
• existence of breastfeeding

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
hyaluronidase	Hyaluronidase Injection mesomedica	-
dexamethasone	Dexamethasone dekort	-

Primary Outcome Measures

Name	Time	Method
evaluation of the increase of edema in postoperative 1. day using a measuring tape in hyaluronidase experimental group	postoperative 1. day	preoperative edema amount was subtracted from edema amount in 1. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 2. day using a measuring tape in hyaluronidase experimental group	postoperative 2. day	preoperative edema amount was subtracted from edema amount in 2. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 3. day using a measuring tape in hyaluronidase experimental group	postoperative 3. day	preoperative edema amount was subtracted from edema amount in 3. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 7. day using a measuring tape in hyaluronidase experimental group	postoperative 7. day	preoperative edema amount was subtracted from edema amount in 7. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 1. day using a measuring tape in hyaluronidase control group	postoperative 1. day	preoperative edema amount was subtracted from edema amount in 1. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 2. day using a measuring tape in hyaluronidase control group	postoperative 2. day	preoperative edema amount was subtracted from edema amount in 2. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 3. day using a measuring tape in hyaluronidase control group	postoperative 3. day	preoperative edema amount was subtracted from edema amount in 3. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 7. day using a measuring tape in hyaluronidase control group	postoperative 7. day	preoperative edema amount was subtracted from edema amount in 7. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 1. day using a measuring tape in dexamethasone experimental group	postoperative 1. day	preoperative edema amount was subtracted from edema amount in 1. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 2. day using a measuring tape in dexamethasone experimental group	postoperative 2. day	preoperative edema amount was subtracted from edema amount in 2. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 3. day using a measuring tape in dexamethasone experimental group	postoperative 3. day	preoperative edema amount was subtracted from edema amount in 3. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 7. day using a measuring tape in dexamethasone experimental group	postoperative 7. day	preoperative edema amount was subtracted from edema amount in 7. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 3. day using a measuring tape in dexamethasone control group	postoperative 3. day	preoperative edema amount was subtracted from edema amount in 3. day in dexamethasone controlgroup
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 1. day using a measuring tape	postoperative 1. day	edema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 1. day
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 2. day using a measuring tape	postoperative 2. day	edema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 2. day
evaluation of the increase of edema in postoperative 1. day using a measuring tape in dexamethasone control group	postoperative 1. day	preoperative edema amount was subtracted from edema amount in 1. day in dexamethasone controlgroup
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 3. day using a measuring tape	postoperative 3. day	edema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 3. day
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 7. day using a measuring tape	postoperative 7. day	edema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 1. day	postoperative 1. day	pain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 2. day	postoperative 2. day	pain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 3. day	postoperative 3. day	pain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 4. day	postoperative 4. day	pain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 5. day	postoperative 5. day	pain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 6. day	postoperative 6. day	pain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 7. day	postoperative 7. day	pain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 1. day	postoperative 1. day	pain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 2. day	postoperative 2. day	pain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 3. day	postoperative 3. day	pain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 4. day	postoperative 4. day	pain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 5. day	postoperative 5. day	pain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the increase of edema in postoperative 2. day using a measuring tape in dexamethasone control group	postoperative 2. day	preoperative edema amount was subtracted from edema amount in 2. day in dexamethasone controlgroup
evaluation of the increase of edema in postoperative 7. day using a measuring tape in dexamethasone control group	postoperative 7. day	preoperative edema amount was subtracted from edema amount in 7. day in dexamethasone controlgroup
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 1. day using a measuring tape	postoperative 1. day	edema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 1. day
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 2. day using a measuring tape	postoperative 2. day	edema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 2. day	postoperative 2. day	pain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 3. day	postoperative 3. day	pain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 4. day	postoperative 4. day	pain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 5. day	postoperative 5. day	pain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 6. day	postoperative 6. day	pain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 3. day using a measuring tape	postoperative 3. day	edema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 3. day
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 7. day using a measuring tape	postoperative 7. day	edema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 6. day	postoperative 6. day	pain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 7. day	postoperative 7. day	pain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 1. day	postoperative 1. day	pain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 2. day	postoperative 2. day	pain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 3. day	postoperative 3. day	pain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 4. day	postoperative 4. day	pain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 5. day	postoperative 5. day	pain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 6. day	postoperative 6. day	pain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 7. day	postoperative 7. day	pain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 1. day	postoperative 1. day	pain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 7. day	postoperative 7. day	pain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group preoperatively.	preoperative	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 1. day.	postoperative 1. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 1. day.	postoperative 1. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 2. day.	postoperative 2. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 3. day.	postoperative 3. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 2. day.	postoperative 2. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 3. day.	postoperative 3. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 7. day.	postoperative 7. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group preoperatively.	preoperative	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 1. day.	postoperative 1. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 2. day.	postoperative 2. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 3. day.	postoperative 3. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 7. day.	postoperative 7. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group preoperatively.	preoperative	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 1. day.	postoperative 1. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 2. day.	postoperative 2. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 3. day.	postoperative 3. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 7. day.	postoperative 7. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group preoperatively.	preoperative	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 7. day.	postoperative 7. day	amount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group preoperatively.	preoperative	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 1. day.	postoperative 1. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 2. day.	postoperative 2. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 3. day.	postoperative 3. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 7. day.	postoperative 7. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group preoperatively.	preoperative	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 1. day.	postoperative 1. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 2. day.	postoperative 2. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 3. day.	postoperative 3. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 7. day.	postoperative 7. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group preoperatively.	preoperative	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 1. day	postoperative 1. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 2. day	postoperative 2. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 3. day	postoperative 3. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 7. day	postoperative 7. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group preoperatively.	preoperatively	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 1. day	postoperative 1. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 2. day	postoperative 2. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 3. day	postoperative 3. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 7. day	postoperative 7. day	existence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.

Trial Locations

Locations (2)

Near East University; 🇨🇾 Nicosia, Cyprus

Hacettepe University; 🇹🇷 Ankara, Sıhhiye, Turkey