Protective role of sedative agents on heart in open heart surgeries.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/06/053644
- Lead Sponsor
- AIIMS JODHPUR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients aged 18 years and above
2. Belonging to American Society of Anaesthesiologists (ASA) physical status II - IV and scheduled for open heart surgery.
3. Patients of either sex.
4. Scheduled for elective open heart surgery.
Exclusion Criteria
1. Emergency surgery
2. Cross-clamp time more than 120 minutes
3. Combined CABG and valvular heart surgery
4. Prior cardiac surgery
5. Left ventricular ejection fraction <0.5
6. Patients having chronic renal/ liver/ pulmonary disease
7. Preoperative mechanical ventilation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Troponin ITimepoint: 24hours
- Secondary Outcome Measures
Name Time Method 1. To compare MB isoenzyme levels between both groups. <br/ ><br>2. To compare need for inotropic and vasopressor support using Vaso-inotropic score(VIS) between both groups. <br/ ><br>3. To compare intra-operative propofol consumption <br/ ><br>4. To compare length of ICU stay. <br/ ><br>5. To compare length of hospital stay. <br/ ><br>6. To compare the survival (at 30 days) <br/ ><br>7. Occurrence of major cardiovascular events within 3 postoperative days.Timepoint: First 72hours postoperative hours