Correlation of clinical outcome with intraarticular cytokine concentrations following cartilage regeneration in knee and upper ankle joint
Recruiting
- Conditions
- M93.2M94.26Osteochondritis dissecans
- Registration Number
- DRKS00000365
- Lead Sponsor
- Schatzmeister der AO Deutschland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
performance of an arthroscopy of the knee joint or the upper ankle joint, patients in the control group have no cartilage lesion in MRI and diagnostic arthroscopy, patients undergoing microfracturing or ACI have full thickness cartilage lesions graded III and IV according to ICRS classification of various size, agreement to participate in the study, age >18 years and <65 years
Exclusion Criteria
alcohol or drug abuse, mental retardation with incapability to complete the necessary self-reports, joint effusion >30ml, persistent knee oder upper ankle joint instability, infection
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ysholm Score, IKDC Score: validated scores about knee function
- Secondary Outcome Measures
Name Time Method oyes Score, the Medical Outcomes Study Short Form-36 (SF-36), and visual analog scales (VAS) for knee pain strength and frequency: parameter for life quality