Comparison of the effect of intraarticular and periarticular injection of cocktail of morphin epinephrin ropivacain ketorolac on eliminating the postoperative pain after total knee arthroplasty in patients with knee degenerative joint disease
Phase 3
Recruiting
- Conditions
- knee degenerative joint disease.
- Registration Number
- IRCT20210613051559N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 96
Inclusion Criteria
those aged 18-80
weight between 50-120 kg
ability to read, write and complete informed consent
Exclusion Criteria
drug sensitivity
drug dependence
neurologic disease
psychiatric illness
cardiac disease
liver disease
cardiac arrythmia
Diabetes
neuromuscular problem
inflammatory arthritis e.g. RA
renal disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of post operative morphin sulfate injection after the total knee arthroplasty. Timepoint: during 72 hr after the total knee arthroplasty. Method of measurement: mg morphin injected by the nursery and documented in the patien's documents.
- Secondary Outcome Measures
Name Time Method Visual analogue scale. Timepoint: during 72 h postoperatively 1 week and 1 months after surgery. Method of measurement: 1 to 10 based on the VAS scale.;WOMAC. Timepoint: 1 DAY before OR, 1 week and 1 month after OR. Method of measurement: womac scale.;KSS. Timepoint: 1 DAY before OR, 1 week and 1 month after OR. Method of measurement: KSS scale.