Bioavailability and effects of soluble phenols of cocoa on inflammatory biomarkers related to atherosclerosis

Completed

• Conditions: Arteriosclerosis; Circulatory System; Atherosclerosis

• Registration Number: ISRCTN75176807
• Lead Sponsor: Ministry of Science and Innovation (Ministerio de Ciencia e Innovación) (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-06-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

1. Males and females between 55 and 80 years old
2. Those without documented cardiovascular disease (ischemic heart disease, stroke, or peripheral vascular disease)
3. Those who have diabetes mellitus or two or more of the following factors:
3.1. Current smoking
3.2. Hypertension
3.3. Hypercholesterolemia (low-density Lipoprotein [LDL]-cholesterol >160 mg/dl)
3.4. High-density lipoprotein (HDL)-cholesterol <40 mg/dl
3.5. Obese (body mass index >30 kg/m^2)
3.6. Family history of premature coronary heart disease
4. Participant should give signed informed consent

Exclusion Criteria

1. Subjects with a previous history of cardiovascular disease (ischemic heart disease, stroke or peripheral vascular disease)
2. Any severe chronic disease
3. History of allergic reactions to any cocoa or milk components

Study & Design

• Study Type: Interventional
• Study Design: Not specified