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临床试验/CTRI/2025/05/086719
CTRI/2025/05/086719尚未招募2/3 期

Single Arm Clinical Study To Assess The Efficacy Of Vidari Kand Kwath InThe Management Of Pittaja Mutrakruchha With Special Reference To Urinary Tract Infection

Sharik Manjur Mulla1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年5月23日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
To see effectiveness of vidari kand kwath in management of pittaja mutrakruchha

研究概览

简要总结

Mutrakruchha is one of common disorder of mutravaha strotas. Mutrakruchha has been documented in the Ayurveda by various scholars; Sushruta samhita, Charaka samhita, Ashtang hruday, Madhava nidan etc.

According to Madhav nidan Mutrakruchha is  painful and difficulty in micturation.

According to Madhav nidan a type of Mutrakruchha; Pittaja Mutrakruchha presents with following symptoms

Yellowish, with blood, painful, with burning sensation, with difficulty and frequent micturation are the symptoms seen in Pittaja Mutrakruchha .            It Is a diseases where difficulty in micturation is due to sadaaha mutrapravruti (Burning sensation), sashool (painful), muhurmuhur mutrapravrutti.  (frequent urination), burning micturation, painful micturition.

Urine is byproduct of blood filtering system that is excretory system, which is performed by kidneys. Kidneys excretes different metabolic wastes that can harm our body with water as a solvent. It also removes excess amount of water. Urine usually drained out without any bacterial or infective contamination, sometimes it gets infected or contaminated which is called as Urinary Tract Infection.

Urinary Tract Infection is any type of infection of whole urinary tract. The urinary system includes Kidneys, Ureters, Urinary bladder, Urethra. Thus Urinary Tract Infection includes infection of above organs, however it usually involves infection of Urinary Bladder and Urethra which is called as Lower Urinary Tract Infection.

As 50-80% of women in general population experience at least one UTI in their lifetime and about 20 to 30% of women will have recurrent UTI.

Prevalence rate of UTI in India is 21 to 31 %(21) as urine is excellent culture for bacteria.

Clinical diagnosis of Urinary Tract Infection is primarily based on medical history which have following symptoms.               Dysuria, nycturia, incontinence over urine, Fever Macrohematuria, suprapubic pain, offensive or foul smell, burning micturation. Symptoms of Urinary Tract Infection are similar to that of Pittaja                            Mutrakruchha. Hence Pittaja Mutrakruchha can be co-related with Urinary Tract Infection.

Vidari, Madhu and Sharkara are common Ayurvedic drugs which are easy to administer. Vidari has other properties such as Balya, Bruhaniya and also is a Pittashamak drug.

This combination of drug administration in Pittaja Mutrakruchha is written in Charak samhita chikitsa and due to above benefits these are selected in management of Pittaja Mutrakruchha.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patient having sign and symptoms of Pittaja Mutrakruchha as per Ayurvedic samhita will be randomly selected .
  • Urine pus cells more than 5 / hpf.
  • RBCs in urine more than 4 / hpf.
  • Symptoms started within 15 days of period.
  • 3 or more symptoms of urinary tract infection from following symptoms and presence of pus cells or RBC (25) Dysuria Macrohematuria Nycturia Suprapubic pain Incontinence over urine Offensive or foul smell.

排除标准

  • Patient with diabetes mellitus.
  • Patients with known case of any systemic disease or urinary calculi.
  • Patient with surgical history of any part of urinary tract.
  • Patients with catheter related urinary tract infection.
  • If crystals in urine are present.

结局指标

主要结局

To see effectiveness of vidari kand kwath in management of pittaja mutrakruchha

时间窗: 15 days

次要结局

  • To observe any adverse effect of vidari kamd kwath in patients of urianry tract infection(15 days)

研究者

发起方
Sharik Manjur Mulla
申办方类型
Other [self]

研究点 (1)

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