Evaluation of the hypnosis effect on accelerating wound healing in oral soft tissue ulcers due to the biopsy.

Phase 4

Conditions: Accelerating of Wound Healing due to Oral Biopsy.

Registration Number: IRCT20180221038808N1

Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 30

Inclusion Criteria

Soft soft tissue lesions include ulcers, reddish white, pigmented, exophytic, requiring biopsy.
Lesions need incisional or excisional biopsy.

Exclusion Criteria

Bad oral hygiene (through a clinical examination)
Having uncontrolled systemic diseases that causes immune system or surgical interference.
Uncontrolled Diabetes, Cushing's disease, or homeostasis problems
Taking medications that delay wound healing (such as taking steroids, etc.)
Having a psychological illness (mental illness)
Cigarette smoking and alcohol and narcotics
Having other oral mucosal diseases (except for a lesion that needs biopsy)
Malignancies (based on histopathologic diagnosis - clinical suspicion - hematologic malignancies)
Lack of proper patient hypnosis
Contraindications to hypnosis and speech or dialect barriers that reject hypnosis interventions
Previous psychosis - severe depression - personality disorders
Previous hypnosis experience

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PHI: Percentage of the healing index: Wound healing index: PHI = 100-PUI. Timepoint: 7 days for acceleration of wound healing. Method of measurement: dentistry Endometer - Photoshop software detects the number of pixels in each ulcer's area.PHI=100- PUI.;PUI: Percentage of the unhealed index: Wound unhealed index: PUI= (T1 / T0) * 100. Timepoint: 7 days for unhealed index. Method of measurement: PUI= (T1/ T0) *100.;T: ulcer size. Timepoint: On the day of biopsy (post-cut)- Seven days after the biopsy (Suture thread opening day). Method of measurement: Endometer - Determining the number of pixels on Photoshop.

Secondary Outcome Measures

Name	Time	Method
Pain. Timepoint: Pain the day before the biopsy- pain on the day of biopsy- pain one day after the biopsy- pain two days after the biopsy. Method of measurement: Visual Analog Scale.;Anxiety. Timepoint: Preoperative- During surgery. Method of measurement: Beck’s questionaries.