ACTRN12610000063011
Completed
Phase 4
A prospective randomized controlled trial to compare postoperative liver functions, cytokines and complications between isoflurane inhaled and propofol intravenous anesthesia in cirrhotic patients undergoing hepatectomy for hepatic carcinoma
Shanghai Rising-Star Program (No 08QA14007)0 sites60 target enrollmentJanuary 19, 2010
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Shanghai Rising-Star Program (No 08QA14007)
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Elective liver resection
- •2\. American Society of Anesthesiologists (ASA) physical status II\-III patients
- •3\. Primary liver cancer patients who had history of hepatitis B related cirrhosis
- •4\. undergoing combined general and epidural anesthesia
Exclusion Criteria
- •1\.Contradictions of epidural puncture including coagulate disorder (prothrombin time (PT) longer than 15 sec or/and blood platelets count less than 10,000\)
- •2\.Tumor size too large or small ( longitude of tumor was beyond 3\-8 cm) or estimated blood loss was large than 1000 cc.
- •3\.Individuals in whom the regional block failed and surgery was performed under general anesthesia alone were also withdrawn from the study.
- •4\.Indivduals fail to be performed Pringer’s maneuver due to technologic problem.
Outcomes
Primary Outcomes
Not specified
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