Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique

Not Applicable

• Conditions: Meniscus Tear
• Interventions: Procedure: Transtibial pullout technique

• Registration Number: NCT03037242
• Lead Sponsor: Mayo Clinic

Brief Summary

The results of this study will optimize the care for patients with a meniscus root tear. Surgeons will be able to determine if MRR (meniscus root repair) with transtibial pullout technique is an effective treatment and will identify potential risk factors for poor clinical outcomes. In addition, investigators will determine if MRR is successful in delaying the radiographic progression of arthritis in the involved compartment.

Detailed Description

The loss of attachment at the root of the meniscus impairs the ability to maintain hoop strain when the tibiofemoral joint is loaded. This loss of hoop strain is responsible for the increased pressure on the articular cartilage.

This new awareness has prompted surgeons to consider surgical repair for treatment of meniscal root avulsions. Despite this recent focus on results of surgical repair, prospective studies are lacking, and the optimal surgical indications and technique have not been optimized.

Study Timeline

• Study First Submitted: 2017-01-26
• Study First Submitted QC: 2017-01-27
• Study First Posted: 2017-01-31
• Study Start: 2017-05-01
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-02
• Last Update Posted: 2025-01-03
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

1. Meniscus root avulsion tear (defined as meniscus posterior horn root avulsion or full thickness tear within 9 mm of the root attachment)
2. Age 18-65
3. Ligament injury with concomitant reconstruction is acceptable
4. Malalignment with corrective osteotomy is acceptable

Exclusion Criteria

1. Subchondral collapse on pre-op MRI
2. Extrusion greater than 3 mm
3. Intra-op Outerbridge grade 3 or greater chondromalacia
4. Intra-op poor quality meniscus tissue
5. Mal-alignment greater than 5 degrees without corrective osteotomy
6. Obesity with BMI over 40
7. Kellgren Lawrence > grade 2
8. Worker's compensation status

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Transtibial pullout technique	Transtibial pullout technique	Evaluation of the clinical and radiographic outcomes for patients undergoing a meniscus root repair (MRR) using a transtibial pullout technique.

Primary Outcome Measures

Name	Time	Method
Change in Tegner activity score	baseline, 2 years	Tegner activity level scale is a graduated list of activities of daily living, recreation, and competitive sports. The patient is asked to select the level of participation that best describes their current level of activity and that before injury. The score varies from 0-10.; A score of 0 represents sick leave or disability pension because of knee problems, whereas a score of 10 corresponds to participation in national and international elite competitive sports \>6 score can only be achieved if the person participates in recreational or competitive sport.

Trial Locations

Locations (2)

Columbia Orthopaedic Group; 🇺🇸 Columbia, Missouri, United States

Mayo Clinic; 🇺🇸 Rochester, Minnesota, United States