Effect of Passive Leg Raising for Fluid Responsiveness
Not Applicable
- Conditions
- Body Fluid RetentionImpedanceCardiac Output, Low
- Registration Number
- NCT02702544
- Lead Sponsor
- Medical University of Warsaw
- Brief Summary
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 - Haemodynamic Measurement System, Medis. GmbH Ilmenau) while lifting the leg at different angles. The measurement lasted 12 minutes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- give voluntary consent to participate in the study
- no clinical cardiovascular disease during the 6 months proceeding entry
Exclusion Criteria
- not meet above criteria
- episode of illness (for example: infection)
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on leg elevation 1 day
- Secondary Outcome Measures
Name Time Method Changes in fluid removal parameter- thoracic fluid content [1/kOhm] during leg elevation 1 day Changes in contractility parameter- acceleration index [1/100/s-2] during leg elevation 1 day Changes in volumetric hemodynamic parameter- stroke volume [ml] induced by fluid removal on leg elevation 1 day Changes in blood pressure values [mmHg] induced by fluid removal on leg elevation 1 day Changes in volumetric hemodynamic parameter- systemic vascular resistance index [dyn·s·cm-5·m-2] induced by fluid removal on leg elevation 1 day Changes in vascular parameter- thoracic arterial complicance [ml/mmHg/m-2] during leg elevation 1 day
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie fluid responsiveness during passive leg raising in patients with low cardiac output and fluid retention?
How does the CardioScreen 1000 compare to standard-of-care methods like echocardiography in assessing volumetric hemodynamic changes during passive leg raising?
Which biomarkers correlate with changes in thoracic fluid content and systemic vascular resistance during passive leg raising in fluid-overloaded patients?
What are the potential adverse events associated with passive leg raising as a hemodynamic intervention in patients with cardiac impairment?
Are there combination therapies or alternative devices that enhance passive leg raising's efficacy in managing fluid overload and improving cardiac index?
Trial Locations
- Locations (1)
Medical University of Warsaw, Department of Emergency Medicine
🇵🇱Warsaw, Masovia, Poland
Medical University of Warsaw, Department of Emergency Medicine🇵🇱Warsaw, Masovia, Poland