Effect of Passive Leg Rasing on Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal

Medical University of Warsaw1 site in 1 country80 target enrollmentMarch 2016

ConditionsBody Fluid Retention Impedance Cardiac Output, Low

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Body Fluid Retention
Sponsor: Medical University of Warsaw
Enrollment: 80
Locations: 1
Primary Endpoint: Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on leg elevation
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 - Haemodynamic Measurement System, Medis. GmbH Ilmenau) while lifting the leg at different angles. The measurement lasted 12 minutes.

Registry

clinicaltrials.gov

Start Date

March 2016

End Date

March 2016

Last Updated

10 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Medical University of Warsaw

Responsible Party

Principal Investigator

Łukasz Szarpak

Principal Investigator

Medical University of Warsaw

Eligibility Criteria

Inclusion Criteria

•give voluntary consent to participate in the study
•no clinical cardiovascular disease during the 6 months proceeding entry

Exclusion Criteria

•not meet above criteria
•episode of illness (for example: infection)
•pregnancy

Outcomes

Primary Outcomes

Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on leg elevation

Time Frame: 1 day

Secondary Outcomes

Changes in fluid removal parameter- thoracic fluid content [1/kOhm] during leg elevation(1 day)
Changes in contractility parameter- acceleration index [1/100/s-2] during leg elevation(1 day)
Changes in volumetric hemodynamic parameter- stroke volume [ml] induced by fluid removal on leg elevation(1 day)
Changes in blood pressure values [mmHg] induced by fluid removal on leg elevation(1 day)
Changes in volumetric hemodynamic parameter- systemic vascular resistance index [dyn·s·cm-5·m-2] induced by fluid removal on leg elevation(1 day)
Changes in vascular parameter- thoracic arterial complicance [ml/mmHg/m-2] during leg elevation(1 day)