MedPath

Danger Signs in Heart Failure- Effects of Video Education

Not Applicable
Completed
Conditions
Heart Failure; With Decompensation
Interventions
Other: Danger Signs of Heart Failure Videos
Registration Number
NCT03657459
Lead Sponsor
The Cleveland Clinic
Brief Summary

Lack of recognition of HF danger signs and lack of understanding of how to control and minimize danger signs could lead to their escalation and prompt all-cause and HF-related health care resource utilization (HCRU). Investigators hypothesize that patients must understand HF danger signs to have self-confidence in recognizing them and in taking steps to minimize or eliminate their occurrence post hospital discharge. Investigators will determine if video education in HF danger signs recognition and control prior to discharge (and post-discharge) reduces all-cause and HF-related HCRU.

Detailed Description

The most frequently cited danger signs of heart failure (HF) are new onset or worsening of fatigue, dyspnea and edema. In previous research, patients did not recognize worsening HF, due to 3 primary reasons: (1) danger signs were non-specific and misinterpreted as stress, an external force or another comorbidity, (2) danger signs were unrecognized due to the subtle nature of worsening status, or (3) when patients eliminated or minimized activities that prompted danger signs, they interpreted the results as improvement in status. Lack of recognition of HF danger signs and lack of understanding of how to control and minimize danger signs could lead to their escalation and prompt all-cause and HF-related health care resource utilization (HCRU). Investigators hypothesize that patients must understand HF danger signs to have self-confidence in recognizing them and in taking steps to minimize or eliminate their occurrence post hospital discharge. The purposes of this trial are to determine if video education in HF danger signs recognition and control prior to discharge (and post-discharge) reduces all-cause and HF-related health care resource utilization. The intervention will be administered during hospitalization, and patients and family members will receive a link to a website and a DVD to review videos as often as desired post-discharge. The primary end-point is 30-day HF-related hospitalization. 732 patients (658 + 10% attrition) with decompensated HF will be enrolled from multiple hospitals.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
746
Inclusion Criteria
  • Not referred for cardiac transplantation or ventricular assist device placement during the index hospitalization,
  • Cognitively intact and able to view videos (adequate eyesight and hearing) with correction, if needed,
  • Discharge to home, assisted living facility or to a family member's home and can control dietary sodium and fluids as needed,
  • Willing to participate; which may require up to three (3) follow-up telephone calls post-discharge.
Exclusion Criteria
  • Chart documented psychiatric or cognitive conditions that limit ability to understand video content or adhere to self-care recommendations (Alzheimer's condition, dementia, schizophrenia, other neurological history that impairs memory or concentration),
  • Plans to discharge to skilled nursing facility or hospice care,
  • Receiving home hospice or palliative care; or has a medical condition reflecting less than 1 year of survival (cachexia, end stage liver disease or cancer or non-ambulatory New York Heart Association functional class IV HF),
  • Hospitalized but at admission, in New York Heart Association functional class I or II HF
  • Post-cardiac transplantation or ventricular assist device placement,
  • Currently enrolled in another experimental HF research study,
  • Chronic renal failure and receiving chronic hemodialysis therapy for an estimated glomerular filtration rate < 15 mL/minute/1.73 m2,
  • A non-traditional form of HF (hypertrophic or restrictive forms of cardiomyopathy, congenital heart disease or Takotsubo cardiomyopathy).

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
video education groupDanger Signs of Heart Failure VideosWill receive usual care, plus will watch 2 short Wellflix, Inc. Danger Signs of Heart Failure videos (via iPAD) on dyspnea, fatigue + a Danger Sign "edema" video, when applicable. Each video describes how to recognize if the sign/symptom is new or worsening and how to self-manage at home (via diet, fluid management and activity instructions)
Primary Outcome Measures
NameTimeMethod
Number of Participants With HF-related Healthcare Resource Utilization (HCRU)up to 30 days

Number of participants post-discharge with HF-related healthcare resource utilization including hospitalization, emergency department (ED) visits, death, or cardiac transplant within 30 days of discharge.

Secondary Outcome Measures
NameTimeMethod
Number of Participants With HF-related ED Visitsup to 30 days

Number of participants with post-discharge HF-related ED visits

Number of Participants With HF-related Deathup to 180 days

Number of participants post-discharge with HF-related death

Number of Participants With HF-related Healthcare Resource Utilization (HCRU)up to 180 days

Number of participants post-discharge with HF-related healthcare resource utilization including hospitalization, emergency department (ED) visits, death, or cardiac transplant within 180 days of discharge.

Number of Participants With All-cause Healthcare Resource Utilization (HCRU)up to 180 days

Number of participants post-discharge with all-cause healthcare resource utilization including hospitalization, emergency department (ED) visits, death, or cardiac transplant within 180 days of discharge.

Number of Participants With HF-related Hospitalizationup to 180 days

Number of participants post-discharge with HF-related hospitalization

Number of Participants With HF-related ED Visitup to 180 days

Number of participants post-discharge with HF-related ED visit

All-cause Death at 180 Days Post Dischargeup to 180 days

Number of participants post-discharge with all-cause death

Number of Participants With All-cause Hospitalizationup to 180 days

Number of participants post-discharge with all-cause hospitalization

Number of Participants With All-cause ED Visitsup to 90 days

Number of participants post-discharge with all-cause ED visits

Number of Participants With All-cause Deathup to 90 days

Number of participants post-discharge with all-cause death

All-cause ED Visits at 180 Daysup to 180 days

Number of participants post-discharge with all-cause ED visits

Functional Status Using the Duke Acrivity Status Index Scale at 30 Days Post Dischargeup to 30 days

Duke Activity Status Index (DASI) score at 30 days. Patients completed the DASI, a 12-item questionnaire using a Likert-like scale that determines a patient's ability to participate in daily self-care activities including ambulation, housework, yard work, sexual relations, and recreational activities. A total score reflects functional status based on responses. The full range of scores is 0 (most severe functional impairment) to 58.2 (no functional impairment). There is no established cut-point for this scale. Positive, higher scores reflect a positive and better functional status.

Dyspnea at 30 Days Post Discharge30 days

PROMIS® Dyspnea Functional Limitations - Short Form 10a was used. It is a 10-item tool that measures dyspnea by asking 10 questions about the difficulty in completing activities in the past 7 days. Responses range from "0 = no difficulty" to "3 = much difficulty" and there is an option for "I did not do this in the past 7 days" - there were 5 response options in total. Minimum and maximum raw scores are 0-30. PROMIS T scores are standardized with scores around 50 (standard deviation of 10) equating to normal/average levels and scores above or below equating to heightening or lessening of the variable being measured. A 5 point change in score is considered significant. A table is used to translate the total raw score to T score for each participant.

Fatigue at 30 Days Post Dischargeto 30 days

10-item Fatigue Assessment Scale from baseline. The Fatigue Assessment Scale is a valid, reliable 10-item scale evaluating symptoms of chronic fatigue. It uses Likert-type response options ranging from 1 ("never") to 5 ("always"), with some items reverse scored. Total scores range from 10 (lowest level of fatigue) to 50 (highest level of fatigue).

Self-efficacy for Managing Symptoms at 30 Days Post Discharge30 days

PROMIS Self-Efficacy for Managing Symptoms Short form 8a for managing symptoms, from baseline. 8-item tool that ranges from 'I am not at all confident' to 'I am very confident" - higher scores equals higher self-efficacy. A mean score of 50 is the average score in the general population of U.S. with standard deviation of 10. A table is used to translate the total raw score to T score for each participant. The T score rescales the raw score into a standardized score with a mean of 50 and a standard deviation of 10. Higher scores (above 50) reflect better than average self-efficacy

Intervention Group Only- All-cause Events Based on Dichotomous Metric of Viewing the Video at Home (Never vs 1+)30 days

Among intervention group participants, total number of all-cause events within 30 days of discharge, based on the number of times the patient watched the video education. Participant responses are grouped into two categories: Never watched vs. 1 or more times

Intervention Group Only; Number of All-cause Events Based on Dichotomous Outcome of Family Member Viewing Educational Video After Hospital Discharge (Yes vs no)30 days

Total number of participants (video education group only), comparison of all-cause events within 30 days of discharge, based on family members watching the educational videos after the hospital (Yes/No).

Trial Locations

Locations (8)

Medical Center Navicent Health

🇺🇸

Macon, Georgia, United States

WellSpan Health

🇺🇸

York, Pennsylvania, United States

Cleveland Clinic Fairview Hospital

🇺🇸

Cleveland, Ohio, United States

Cleveland Clinic South Pointe Hospital

🇺🇸

Warrensville Heights, Ohio, United States

Cleveland Clinic Medina Hospital

🇺🇸

Medina, Ohio, United States

Cleveland Clinic main campus

🇺🇸

Cleveland, Ohio, United States

Cleveland Clinic Marymount Hospital

🇺🇸

Garfield Heights, Ohio, United States

Cleveland Clinic Hillcrest Hospital

🇺🇸

Mayfield Heights, Ohio, United States

© Copyright 2025. All Rights Reserved by MedPath