Observational - Relationships Between Tumor-Associated Macrophages and Clinicopathological Factors in Wilms Tumor
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Relationship of tumor-associated macrophages and prognosis
研究概览
简要总结
This research study is studying biomarkers in tissue samples from younger patients with Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment
详细描述
PRIMARY OBJECTIVES:
I. To determine whether recruitment of tumor-associated macrophages is related to clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion, tumor progression, and survival).
OUTLINE:
Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample are then compared with patient's tumor stage, presence of vascular invasion, tumor progression, and survival.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Wilms tissue microarray samples provided by the Children's Oncology Group
排除标准
- 未提供
结局指标
主要结局
Relationship of tumor-associated macrophages and prognosis
时间窗: 1 month
Correlation of each type of macrophage score with tumor staging, presence of vascular invasion, and disease-free survival will be assessed.
次要结局
未报告次要终点