Treatment of gum disease in patients with diabetes mellitus
Completed
- Conditions
- Diabetes mellitus (DM), periodontitis (PD)Nutritional, Metabolic, EndocrineNon-insulin-dependent diabetes mellitus
- Registration Number
- ISRCTN00559156
- Lead Sponsor
- niversity of Perugia (Università degli Studi di Perugia) (Italy)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
1. Aged 35 to 70 years, either sex
2. Type 1 and 2 diabetes at the department of Endocrinology of Perugia Hospital
3. Presenting with mild to moderate periodontitis (defined as at least six sites in the mouth exhibited probing depths equal or greater than 4 mm; in each patient, bone loss was confirmed by an radiographic assessment)
Exclusion Criteria
1. Presenting with signs of acute infections
2. Uncontrolled diabetes complications
3. Infectious diseases such as hepatitis or human immunodeficiency virus (HIV) infection
4. Patients requiring antibiotic prophylaxis before dental procedures
5. Patients who received a course of systemic antibiotic or periodontal therapy within the preceding 3 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in HbA1c after 8 months of therapy between cases and controls.
- Secondary Outcome Measures
Name Time Method Changes in periodontal parameters after therapy between cases and controls, recorded at baseline, 4 and 8 months after periodontal therapy.