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Clinical Trials/NCT01207700
NCT01207700
Completed
N/A

A Randomized, Open Trial Comparing Post Discharge Interventions to Standard Care

St. John's Research Institute13 sites in 1 country806 target enrollmentAugust 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acute Coronary Syndrome
Sponsor
St. John's Research Institute
Enrollment
806
Locations
13
Primary Endpoint
To obtain estimates of rates of adherence to pharmacotherapy and lifestyle modification interventions and the incidence of major cardiovascular events
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

This is a randomized, open trial comparing post discharge interventions by community health workers (CHW) to standard care in acute coronary syndrome (ACS) patients.

This trial will be conducted in 10 hospitals in India/different parts(both secondary and tertiary care). A total of 800 patients will be recruited, with equal allocation to SPREAD interventions and control groups (usual care)

Detailed Description

Inclusion criteria: Consenting patients being discharged after an acute coronary event such as unstable angina, acute myocardial infarction, or after coronary intervention (CABG surgery or PCI). Exclusion criteria: Patients with other terminal/ debilitating illness, (e.g., advanced cancer, disabling stroke) those not expected to survive for the study duration, those with dementia and psychiatric illness or patients unlikely to comply with study requirements, including regular follow up. OUTCOME MEASURES: 1. Feasibility 2. Difference in adherence to specific medications for secondary prevention of CAD (Coronary Artery Diseases) compared to the control group, at one year.

Registry
clinicaltrials.gov
Start Date
August 2011
End Date
August 2013
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr Alben Sigamani

Associate Professor

St. John's Research Institute

Eligibility Criteria

Inclusion Criteria

  • Consenting patients being discharged after an acute coronary event such as unstable angina, acute myocardial infarction, or after coronary intervention (CABG surgery or PCI).

Exclusion Criteria

  • Patients with other terminal/ debilitating illness, (e.g., advanced cancer, disabling stroke) those not expected to survive for the study duration, those with dementia and psychiatric illness or patients unlikely to comply with study requirements, including regular follow up

Outcomes

Primary Outcomes

To obtain estimates of rates of adherence to pharmacotherapy and lifestyle modification interventions and the incidence of major cardiovascular events

Time Frame: 12 months

Evaluate the rates of adherence to pharmacotherapy and lifestyle modifications using the community health worker

To determine the feasibility of conducting a secondary prevention trial using CDCHWs on adherence to medications and lifestyle advice

Time Frame: 12 MONTHS

A pilot study to look at feasibiility of using a trained community health worker to deliver health messages to patients who have had a coronary event

Study Sites (13)

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