BioDulse: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Healthy Adults
Not Applicable
Completed
- Conditions
- Healthy
- Interventions
- Dietary Supplement: Seaweed protein
- Registration Number
- NCT05850429
- Lead Sponsor
- University of Limerick
- Brief Summary
Co-ingesting protein with carbohydrate is an effective way to improve postprandial glucose handling. The investigators have isolated and identified a bioactive protein extracted from seaweed. The investigators aim to explore how varying doses of seaweed protein influence postprandial glycaemia and insulinaemia in a healthy population.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 11
Inclusion Criteria
- Aged 18-67
Exclusion Criteria
- Terminal disease
- Past medical history of vascular disease, cancer, diabetes, neurological, kidney, pulmonary, digestive (Coeliac disease), thyroidal disease, cognitive impairment;
- Exclusively receiving enteral or parenteral nutrition,
- Any conditions/anomalies that are contraindications to bioelectrical impedance analysis as per institutional risk assessment and SOP.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Medium protein Seaweed protein 0.6g/kg body mass maltodextrin PLUS 0.15g/kg body mass protein from Biodulse, in solution Control Seaweed protein 0.6g/kg body mass maltodextrin in solution. Low protein Seaweed protein 0.6g/kg body mass maltodextrin PLUS 0.075g/kg body mass protein from Biodulse, in solution
- Primary Outcome Measures
Name Time Method Postprandial blood glucose area under the curve (AUC) 120 min Integrated area under curve of blood glucose concentration (measured as mmol/L) over 120min
- Secondary Outcome Measures
Name Time Method Timecourse of blood glucose concentration 0, 15, 30, 45, 60, 90, 120 min Timecourse of blood glucose concentration (measured as mmol/L)
Postprandial serum insulin concentration 0, 15, 30, 45, 60, 90, 120 min Timecourse of serum insulin concentration (measured as mU/L)
Postprandial serum insulin area under the curve (AUC) 120 min Integrated area under curve of blood glucose concentration (measured as mU/L) over 120min
Trial Locations
- Locations (1)
University of Limerick
🇮🇪Limerick, Ireland