Prevalence and the relationship between vitamin D deficiency and inflammatory markers among adult outpatients with depressio
- Conditions
- vitamin D deficiency in adult outpatients with depression.Vitamin D deficiency, depression, prevalence, inflammatory marker
- Registration Number
- TCTR20221231006
- Lead Sponsor
- Quality Improvement Fund, King Chulalongkorn Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
1. Aged 18-60 years old
2. Depressive disorder was diagnosed base on DSM-5 criteria
Exclusion Criteria
1.CKD stage III-V
2.Primary hyperparathyroidism
3.Granulomatous disease
4.GI malabsorption: short bowel syndrome, pancreatitis, IBD, bariatric surgery
5.Liver disease
6.Renal insufficiency or nephrotic syndrome
7.Medication history which affects vitamin D levels in one year
- Antineoplastic drugs: cyclophosphamide, taxol, tamoxifen
- Antibiotic and antifungal: clotrimazole, rifampicin
- Anti-inflammatory agents: dexamethasone
- Anti-hypertensive drug: nifedipine, spironolactone
- Antiretroviral drugs: Ritonavir
- Endocrine drugs: Cyproterone acetate
8. Pregnancy and lactation
9. Vitamin D supplement
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vitamin D deficiency The time point in which depression severity was assessed 25(OH)D measured by CLIA
- Secondary Outcome Measures
Name Time Method Relationship between vitamin D deficiency and inflammatory marker The time point in which depression severity was assessed Blood for CRP and relationship was measured by Logistic Regression (Odds Ratio) by SPSS