Prevalence of vitamin D defiency, its determinants and associations with health factors in infants and toddlers in the Netherlands
Recruiting
- Conditions
- 'vitamin D deficiency' and 'hypovitaminosis D'10047635
- Registration Number
- NL-OMON41767
- Lead Sponsor
- Meander Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 800
Inclusion Criteria
- aged between 6 months and 4 years
- visiting the 'consultatiebureau' in the measurement period
Exclusion Criteria
• Malabsorption by coeliakie, cystic fibrosis and inflamatory bowel disease
• Chronic liver or kidney disease
• Medication influencing vitamin D metabolism like oral glucocorticosteroïds and anticonvulsivants
• Contra-indication for drawing blood
• Impaired immunostatus, HIV/AIDS/TBC
• Osteogenesis imperfecta
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>By capillary blood drawing followed by analysis with the Dried Blood Spot<br /><br>methode the 25(OH)D status will be determined. Rachitic symptoms, infectious<br /><br>airway diseases, growth, weight status, and motoric development will be<br /><br>determined by physical examination.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Recent history of infectious diseases, oral hygiene, exposure to sunlight, skin<br /><br>color, dietary and supplementary vitamin D will be assessed by questionnaire. </p><br>