Natural Course and Prognosis of Hospitalized Patients With Cirrhosis: a Prospective, Multicenter, and Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 336
- 试验地点
- 4
- 主要终点
- All-cause mortality
研究概览
简要总结
The aim of this prospective study is to evaluate the natural course and prognosis of hospitalized patients with liver cirrhosis.
详细描述
The aim of this prospective study is to collect data on hospitalized patients with liver cirrhosis at four institutions in Korea (Kangbuk Samsung Hospital, Hallym University Dongtan Sacred Heart Hospital, Chosun University Hospital, and National Medical Center). If patients agree to participate in this clinical trial, the patients' data (such as age, sex, height, weight, nutrition status [RFH-NPT], history of medication, laboratory findings, endoscopic findings, and radiologic findings) will be collected in a research database. The research database will be updated, every 6 months, to include data on patients' disease outcomes and follow-up care.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized patients with liver cirrhosis
- •Admission to the hospital because of cirrhotic complications such as uncontrolled ascites, variceal bleeding, hepatic encephalopathy, hepatorenal syndrome, spontaneous bacterial peritonitis, hepatocellular carcinoma, acute kidney injury, bacterial infection, acute liver failure, and etc.
排除标准
- •Admission to the hospital without cirrhotic complications
- •Patients who refuse the follow-up of outpatient department
结局指标
主要结局
All-cause mortality
时间窗: Up to 2 years
Death from any cause
Liver-related mortality
时间窗: Up to 2 years
Death from liver disease
次要结局
- Cause of admission to hospital(At baseline)
研究者
Won Sohn
Principal Investigator
Kangbuk Samsung Hospital