Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and Phantom Limb Pain Development in Patients Undergoing Lower Limb Amputation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Phantom Limb Pain
- Sponsor
- DIMITRIOS KATSAROS
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- Presence of phantom limb pain
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The goal of this observational study is to determine the effect of femoral and sciatic nerve blocks, combined with general anesthesia, in postoperative pain levels and phantom limb pain development in patients undergoing lower limb amputation.
Investigators
DIMITRIOS KATSAROS
Dimitrios Katsaros, MD
G.Gennimatas General Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing lower limb amputation 10cm cephalad or 10cm caudal of the knee, due to Peripheral Arterial Disease
Exclusion Criteria
- •Any form of dementia
- •Prior chronic neuropathic pain as assessed with DN4 questionnaire
- •Surgery under neuraxial anaesthesia
- •Inability to complete a Numeric Rating Scale to assess pain
- •Contraindication to ropivacaine
Outcomes
Primary Outcomes
Presence of phantom limb pain
Time Frame: Total screening time up to 9 months from day of surgery (DAY 0). Timeframe: DAY 3, DAY 7, DAY 30, DAY 60, DAY 90, DAY 120, DAY 150, DAY 180, DAY 210, DAY 240, DAY 270.
Presence of phantom limp pain and residual limp pain assessed using the painDETECT questionnaire (total scoring 0-38, 0-12 indicating an unlikely component of neuropathic pain, 13-18 an ambiguous result and 19-38 a likely component of neuropathic pain) for neuropathic pain
Secondary Outcomes
- Postoperative morphine consumption(Up to 3 days after surgery (DAY 0), i. e. until DAY 3)
- Postoperative pain(Up to 3 days after day of surgery (DAY 0). Assessed at: DAY 0 12 hours after end of surgery, DAY 1 , DAY 2, DAY 3)