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Clinical Trials/NCT02387021
NCT02387021
Unknown
Not Applicable

Prospective Comparison Between Continuous Femoral Nerve Block and the Association of Adductor Canal Block and Sciatic Nerve Block in Total Knee Arthroplasty.

Institut Kassab d'Orthopédie0 sites80 target enrollmentMarch 2015

Overview

Phase
Not Applicable
Intervention
Continuous femoral nerve block
Conditions
Neuromuscular Blockade
Sponsor
Institut Kassab d'Orthopédie
Enrollment
80
Primary Endpoint
Total Opioid-consumption
Last Updated
11 years ago

Overview

Brief Summary

The purpose of the study is to determine whether the association of sciatic nerve block to continuous adductor canal block is effective in the treatment of total knee arthroplasty post operative pain .

Registry
clinicaltrials.gov
Start Date
March 2015
End Date
December 2015
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Institut Kassab d'Orthopédie
Responsible Party
Principal Investigator
Principal Investigator

Rais Karim

Dr

Institut Kassab d'Orthopédie

Eligibility Criteria

Inclusion Criteria

  • Elective unilateral TKA,
  • Planned continuous spinal anesthesia ,
  • Ability to follow study protocol,
  • American Society of Anesthesiologists class 1 to 3.

Exclusion Criteria

  • Contraindication for neuraxial anesthetic,
  • Chronic opioid use (defined as daily or almost daily use of opioids for \>3 months),
  • Hypersensitivity and/or allergies to any of the study medications,
  • Intraoperative use of volatile anesthetics,
  • Preexisting neuropathy on the operative limb,
  • Contraindications to a femoral, adductor canal or Tibial nerve block.

Arms & Interventions

Continous femoral nerve block

Patients will receive ultrasound-guided (USG) continuous femoral nerve block with 20 ml ropivacaine 0.2% and USG Continuous adductor canal block with 20 ml of saline and USG infragluteal SNB with 20 ml of saline .

Intervention: Continuous femoral nerve block

Continous femoral nerve block

Patients will receive ultrasound-guided (USG) continuous femoral nerve block with 20 ml ropivacaine 0.2% and USG Continuous adductor canal block with 20 ml of saline and USG infragluteal SNB with 20 ml of saline .

Intervention: Continuous adductor canal block

Continous femoral nerve block

Patients will receive ultrasound-guided (USG) continuous femoral nerve block with 20 ml ropivacaine 0.2% and USG Continuous adductor canal block with 20 ml of saline and USG infragluteal SNB with 20 ml of saline .

Intervention: infragluteal Sciatic nerve block

Continous femoral nerve block

Patients will receive ultrasound-guided (USG) continuous femoral nerve block with 20 ml ropivacaine 0.2% and USG Continuous adductor canal block with 20 ml of saline and USG infragluteal SNB with 20 ml of saline .

Intervention: Ropivacaine 0.2%

Continous femoral nerve block

Patients will receive ultrasound-guided (USG) continuous femoral nerve block with 20 ml ropivacaine 0.2% and USG Continuous adductor canal block with 20 ml of saline and USG infragluteal SNB with 20 ml of saline .

Intervention: Saline

Continuous adductor canal block

Patients will receive ultrasound-guided continuous adductor canal block with 20 ml ropivacaine 0.2% and USG infragluteal SNB with 20 ml ropivacaine 0.2% and USG continuous FNB with 20 ml of saline .

Intervention: Continuous femoral nerve block

Continuous adductor canal block

Patients will receive ultrasound-guided continuous adductor canal block with 20 ml ropivacaine 0.2% and USG infragluteal SNB with 20 ml ropivacaine 0.2% and USG continuous FNB with 20 ml of saline .

Intervention: Continuous adductor canal block

Continuous adductor canal block

Patients will receive ultrasound-guided continuous adductor canal block with 20 ml ropivacaine 0.2% and USG infragluteal SNB with 20 ml ropivacaine 0.2% and USG continuous FNB with 20 ml of saline .

Intervention: infragluteal Sciatic nerve block

Continuous adductor canal block

Patients will receive ultrasound-guided continuous adductor canal block with 20 ml ropivacaine 0.2% and USG infragluteal SNB with 20 ml ropivacaine 0.2% and USG continuous FNB with 20 ml of saline .

Intervention: Ropivacaine 0.2%

Continuous adductor canal block

Patients will receive ultrasound-guided continuous adductor canal block with 20 ml ropivacaine 0.2% and USG infragluteal SNB with 20 ml ropivacaine 0.2% and USG continuous FNB with 20 ml of saline .

Intervention: Saline

Outcomes

Primary Outcomes

Total Opioid-consumption

Time Frame: 8 hours postoperative

Cumulative opioid consumption : converting oral, intravenous, and patient-controlled analgesia PCA opioid to morphine equivalent

Secondary Outcomes

  • NRS pain score at rest(0,1,2,4,6,8,12,24 and 48 hours postoperative)
  • NRS pain score during movement(0,1,2,4,6,8,12,24 and 48 hours postoperative)
  • patient satisfaction(8, 24 and 48 hours postoperative)
  • Ability to walk(8, 24 and 48 hours postoperative)
  • NRS pain score after 10 meters of walk or maximum walked distance(8, 24 and 48 hours postoperative)
  • TUG Test(8, 24 and 48 hours postoperative)
  • The 10-m walk test(8, 24 and 48 hours postoperative)

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